Enantioselective synthesis and determination of the absolute configuration of natural (-)-elegansidiol

被引：0
|
作者：
Audran, G [1 ]
Galano, JM [1 ]
Monti, H [1 ]
机构：
[1] Fac Sci & Tech St Jerome, CNRS, UMR 6516, Lab React Organ Select, F-13397 Marseille 20, France
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 2001卷 / 12期
关键词：
asymmetric synthesis; configuration determination; domino reactions; natural products;
D O I：
10.1002/1099-0690(200106)2001:12<2293::AID-EJOC2293>3.0.CO;2-E
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The enantioselective synthesis and determination of the absolute configuration of the title compound (-)-1 has been carried out starting from karahana lactone (+)-2 as an enantiopure building block. The structure was confirmed by single crystal X-ray diffraction analysis and the optical purity of (-)(1S,3R)-elegansidiol (-)-1 verified by chiral HPLC.
引用
收藏
页码：2293 / 2296
页数：4
相关论文
共 50 条
  • [41] TOTAL SYNTHESIS AND ABSOLUTE CONFIGURATION OF NATURAL MULTIFLORAMINES
    BROSSI, A
    OBRIEN, J
    TEITEL, S
    HELVETICA CHIMICA ACTA, 1969, 52 (03) : 678 - &
  • [42] Enantioselective total synthesis of the novel tricyclic sesquiterpene (-)-sulcatine G. Absolute configuration of the natural product
    Mehta, G
    Sreenivas, K
    TETRAHEDRON LETTERS, 2002, 43 (18) : 3319 - 3321
  • [43] Enantioselective total syntheses and determination of absolute configuration of marine toxins, oxazinins
    Dethe, Dattatraya H.
    Ranjan, Alok
    RSC ADVANCES, 2013, 3 (45): : 23692 - 23703
  • [44] Total Synthesis of (+)-Perophoramidine and Determination of the Absolute Configuration
    Wu, Haoxing
    Xue, Fei
    Xiao, Xue
    Qin, Yong
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (40) : 14052 - 14054
  • [45] Total Synthesis and Determination of the Absolute Configuration of (-)-Dolabriferol
    Laclef, Sylvain
    Turks, Maris
    Vogel, Pierre
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (45) : 8525 - 8527
  • [46] Total Synthesis and Determination of the Absolute Configuration of (-)-Idesolide
    Yamakoshi, Hiroyuki
    Shibuya, Masatoshi
    Tomizawa, Masaki
    Osada, Yuji
    Kanoh, Naoki
    Iwabuchi, Yoshiharu
    ORGANIC LETTERS, 2010, 12 (05) : 980 - 983
  • [47] RESOLUTION OF (+-)-ZEARALENONE . DETERMINATION OF ABSOLUTE CONFIGURATION OF NATURAL ENANTIOMORPH
    KUO, CH
    TAUB, D
    HOFFSOMM.RD
    WENDLER, NL
    CHEMICAL COMMUNICATIONS, 1967, (15) : 761 - &
  • [48] Total synthesis and determination of the absolute configuration of rakicidin A
    Chen, Yue, 1600, American Chemical Society (136):
  • [49] Stereoselective Synthesis and Absolute Configuration Determination of Xylariolide A
    Manuel Botubol, Jose
    Macias-Sanchez, Antonio J.
    Collado, Isidro G.
    Hernandez-Galan, Rosario
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 2013 (12) : 2420 - 2427
  • [50] Total Synthesis and Determination of the Absolute Configuration of Parimycin
    Hsu, Day-Shin
    Huang, Jiun-Yi
    ORGANIC LETTERS, 2019, 21 (18) : 7665 - 7668
12345