Gas-Cell Referenced Swept Source Phase Sensitive Optical Coherence Tomography

被引:12
|
作者
Kuranov, Roman V. [1 ]
McElroy, Austin B. [2 ]
Kemp, Nate [2 ]
Baranov, Stepan [3 ]
Taber, Joe [2 ]
Feldman, Marc D. [4 ]
Milner, Thomas E. [5 ]
机构
[1] Volcano Corp, San Antonio, TX 78247 USA
[2] Volcano Corp, Billerica, MA USA
[3] Univ Houston, Dept Biomed Engn, Houston, TX 77204 USA
[4] Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA
[5] Univ Texas Austin, Dept Biomed Engn, Austin, TX 78712 USA
关键词
Biomedical optical imaging; optical coherence tomography (OCT); phase measurements; SPEED; FLOW; NANOPARTICLES; TISSUE; BLOOD;
D O I
10.1109/LPT.2010.2055842
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Distinct reference and signal interferometers in combination with a gas-cell spectral reference are employed to increase sensitivity and environmental stability of a swept source phase-sensitive optical coherence tomography. A displacement sensitivity (DS) of 65 pm at 280-mu m depth and DS degradation with depth of 0.0015 rad/mm is achieved. Differential DS of 234 pm in a 127-mu m-thick scattering phantom is six-fold superior to previously reported values. DS degradation with a depth of 0.026 rad/mm is reported for tissue-like scattering phantoms. Measured depth-dependent DS suggests that digitization time jitter noise contributes to degradation of phase sensitivity with depth.
引用
收藏
页码:1524 / 1526
页数:3
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