Role of 1,4-benzothiazine derivatives in medicinal chemistry

被引：41

作者：

Fringuelli, R ^{[1
]}

Milanese, L ^{[1
]}

Schiaffella, F ^{[1
]}

机构：

[1] Univ Perugia, Dept Drug Chem & Technol, I-06123 Perugia, Italy

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2005年 / 5卷 / 12期

关键词：

D O I：

10.2174/138955705774933365

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

1,4-Benzothiazine (1,4-BT) derivatives have been reported to exhibit a wide range of pharmacological properties including antifungal, immunostimulating, anti-aldoso-reductase, anti-rheumatic, anti-allergic, vasorelaxant, anti-arrhythmic, anti-hypertensive, neuroprotective and cytotoxic activities. These different effects indicate that 1,4-BT is a template potentially useful in medicinal chemistry research and therapeutic applications.

引用

页码：1061 / 1073

页数：13

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