Role of 1,4-benzothiazine derivatives in medicinal chemistry

被引：41
|
作者：
Fringuelli, R [1 ]
Milanese, L [1 ]
Schiaffella, F [1 ]
机构：
[1] Univ Perugia, Dept Drug Chem & Technol, I-06123 Perugia, Italy
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2005年 / 5卷 / 12期
关键词：
D O I：
10.2174/138955705774933365
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
1,4-Benzothiazine (1,4-BT) derivatives have been reported to exhibit a wide range of pharmacological properties including antifungal, immunostimulating, anti-aldoso-reductase, anti-rheumatic, anti-allergic, vasorelaxant, anti-arrhythmic, anti-hypertensive, neuroprotective and cytotoxic activities. These different effects indicate that 1,4-BT is a template potentially useful in medicinal chemistry research and therapeutic applications.
引用
收藏
页码：1061 / 1073
页数：13
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