Odontogenic effects of a fast-setting calcium-silicate cement containing zirconium oxide

被引:8
|
作者
Kim, Kyoung-A [1 ,2 ]
Yang, Yeon-Mi [3 ,4 ]
Kwon, Young-Sun [1 ,2 ]
Hwang, Yun-Chan [5 ]
Yu, Mi-Kyung [1 ,2 ,6 ]
Min, Kyung-San [1 ,2 ,6 ]
机构
[1] Chonbuk Natl Univ, Sch Dent, Dept Conservat Dent, Jeonju Si 561756, Jeollabuk Do, South Korea
[2] Chonbuk Natl Univ, Inst Oral Biosci, Jeonju Si 561756, Jeollabuk Do, South Korea
[3] Chonbuk Natl Univ, Sch Dent, Dept Pediat Dent, Jeonju Si 561756, Jeollabuk Do, South Korea
[4] Chonbuk Natl Univ, Inst Oral Biosci, Jeonju Si 561756, Jeollabuk Do, South Korea
[5] Chonnam Natl Univ, Sch Dent, Dept Conservat Dent, Gwangju Si, South Korea
[6] Chonbuk Natl Univ, Res Inst Clin Med, Biomed Res Inst, Chonbuk Natl Univ Hosp, Jeonju Si 561756, Jeollabuk Do, South Korea
基金
新加坡国家研究基金会;
关键词
Primary dental pulp; Calcium silicate; Mineral trioxide aggregate; Reparative dentin; Zirconium; MINERAL TRIOXIDE AGGREGATE; DENTAL-PULP CELLS; WHITE PORTLAND-CEMENT; 2-YEAR FOLLOW-UP; BISMUTH OXIDE; PRIMARY TEETH; HYDRATION ACCELERATORS; PHYSICAL-PROPERTIES; CAPPING MATERIAL; BIOCOMPATIBILITY;
D O I
10.4012/dmj.2014-154
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
A fast-setting calcium-silicate cement (Endocem) was introduced in the field of dentistry for use in vital pulp therapy. Similar to mineral trioxide aggregate (MTA), it contains bismuth oxide to provide radiopacity. Recently, another product, EndocemZr, which contains zirconium oxide (ZrO2) as a radiopacifier, was developed by the same company. In this study, the biological/odontogenic effects of EndocemZr were investigated in human primary dental pulp cells (hpDPCs) in vitro and on capped rat teeth in vivo. The biocompatibility of EndocemZr was similar to that of ProRoot and Endocem on the basis of cell viability tests and cell morphological analysis. The mineralization nodule formation, expression of odontogenic-related markers, and reparative dentin formation of EndocemZr group was similar to those of other material groups. Our results suggest that EndocemZr has the potential to be used as an effective material for vital pulp therapy, similar to ProRoot and Endocem.
引用
收藏
页码:432 / 440
页数:9
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