Upfront Addition of Sorafenib and Cladribine Based Chemotherapy in FMS-Like-Tyrosine Kinase-3 Internal Tandem Duplication (FLT3-ITD) Mutated Pediatric-Acute Myeloid Leukemia (AML): A Single Centre Experience

被引：0
|
作者：
Pradhan, N. D. [1 ]
Vijaysekharan, K. [1 ]
Tandon, S. [1 ]
Sankaran, H. [1 ]
Prasad, M. [1 ]
Narula, G. [1 ]
Patkar, N. [2 ]
Tembhare, P. [2 ]
Subramanian, P. G. [2 ]
Banavali, S. [1 ]
机构：
[1] Tata Mem Ctr Med Oncol Pediat, Bombay, Maharashtra, India
[2] Tata Mem Hosp, Hematopathol Lab, Bombay, Maharashtra, India
来源：
PEDIATRIC BLOOD & CANCER | 2018年 / 65卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
PO-207
引用
收藏
页码：S187 / S187
页数：1
相关论文
共 50 条
  • [1] Activating internal tandem duplication mutations of the fms-like tyrosine kinase-3 (FLT3-ITD) at complete response and relapse in patients with acute myeloid leukemia
    Nazha, Aziz
    Cortes, Jorge
    Faderl, Stefan
    Pierce, Sherry
    Daver, Naval
    Kadia, Tapan
    Borthakur, Gautam
    Luthra, Raja
    Kantarjian, Hagop
    Ravandi, Farhad
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2012, 97 (08): : 1242 - 1245
  • [2] Sorafenib Combined with Non-Conventional Chemotherapy Produces Deep Remissions in FMS-like Tyrosine Kinase-3 Gene / Internal Tandem Duplication Positive (FLT-3 / ITD+) Acute Myeloid Leukemia (AML) Patients
    Banavali, Shripad
    Thacker, Nirav
    Arora, Brijesh
    Narula, Gaurav
    Prasad, Maya
    Pradhan, Nirmalya
    Panda, Saroj
    Patkar, Nikhil
    Tembhare, Prashant
    Subramanian, Papagudi Ganesan
    BLOOD, 2015, 126 (23)
  • [3] Targeting DNA Damage and Repair in Acute Myeloid Leukemia Carrying Internal Tandem Duplication of Fms-like Tyrosine Kinase 3 (FLT3-ITD) - a Mechanistic Study
    Nelson, Ka Lam
    Lynn, Claire
    Leung, Thomas Wing Yan
    So, Eric Chi Wai
    Leung, Anskar Yu Hung
    BLOOD, 2019, 134
  • [4] SORAFENIB COMBINED WITH NON-CONVENTIONAL CHEMOTHERAPY PRODUCES DEEP REMISSIONS IN FMS-LIKE TYROSINE KINASE-3 GENE/INTERNAL TANDEM DUPLICATION POSITIVE (FLT-3/ITD+) POSITIVE ACUTE MYELOID LEUKEMIA (AML) PATIENTS
    Thacker, Nirav
    Banavali, Shripad
    Arora, Brijesh
    Narula, Gaurav
    Prasad, Maya
    Patkar, Nikhil
    Tembhare, Prashant
    Subramanian, P. G.
    PEDIATRIC BLOOD & CANCER, 2016, 63 : S29 - S29
  • [5] Prognostic Role of Multiparameter Flow Cytometry-Based Measurable Residual Disease Assessment in Acute Myeloid Leukemia Patients with FMS3-like Tyrosine Kinase-3 Internal Tandem Duplication (FLT3-ITD)
    Lucero, Josephine Anne
    Bankar, Aniket
    Davidson, Marta Beata
    Richard-Carpentier, Guillaume
    Schimmer, Aaron D.
    Schuh, Andre C.
    Maze, Dawn C.
    Yee, Karen
    Minden, Mark D.
    Chan, Steven M.
    Mattsson, Jonas
    Kumar, Rajat
    Gupta, Vikas
    Capo-Chichi, Jose-Mario
    Stockley, Tracy
    Sibai, Hassan
    Tierens, Anne Maria
    Kim, Dennis Dong Hwan
    BLOOD, 2023, 142
  • [6] Sorafenib in Relapsed AML With FMS-Like Receptor Tyrosine Kinase-3 Internal Tandem Duplication Mutation
    Giri, Smith
    Hamdeh, Shadi
    Bhatt, Vijaya Raj
    Schwarz, James K.
    JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2015, 13 (05): : 508 - 514
  • [7] The Pim kinase inhibitor AZD1208 sensitizes acute myeloid leukemia cells with fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) to cytotoxic effects of chemotherapy drugs
    Doshi, Kshama A.
    Natarajan, Karthika
    Wolfson, Benjamin
    Huszar, Dennis
    Baer, Maria R.
    CANCER RESEARCH, 2015, 75
  • [8] Pretreatment FMS like Tyrosine kinase-3 Internal Tandem duplication (FLT3-ITD) Mutant Allele Burden Does Not Predict Response to the Combination of Sorafenib and Azacytidine in Patients with Relapsed or High Risk Elderly Untreated Acute Myeloid Leukemia
    George, Binsah
    Cortes, Jorge
    Cabrera, Monica
    Jain, Nitin
    Konopleva, Marina
    Andreeff, Michael
    Tapan, Kadia
    Pierce, Sherry
    Dellasala, Sara
    Borthakur, Gautham
    Jabbour, Elias
    Garcia-Manero, Guillermo
    Kantarjian, Hagop
    Ravandi, Farhad
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2015, 15 : S196 - S197
  • [9] Sorafenib-induced Thyroiditis in FMS-like Tyrosine Kinase 3-internal Tandem Duplication-mutated Acute Myeloid Leukemia
    Jie Sun
    Juan Hu
    Yan Huang
    Shuang-Wei Ying
    Xiao-Yan Han
    Yan-Long Zheng
    He Huang
    中华医学杂志英文版, 2016, 129 (20) : 2512 - 2513
  • [10] Sorafenib-induced Thyroiditis in FMS-like Tyrosine Kinase 3-internal Tandem Duplication-mutated Acute Myeloid Leukemia
    Sun, Jie
    Hu, Juan
    Huang, Yan
    Ying, Shuang-Wei
    Han, Xiao-Yan
    Zheng, Yan-Long
    Huang, He
    CHINESE MEDICAL JOURNAL, 2016, 129 (20) : 2512 - 2513
12345