Sorafenib-induced Thyroiditis in FMS-like Tyrosine Kinase 3-internal Tandem Duplication-mutated Acute Myeloid Leukemia

被引:0
|
作者
Jie Sun [1 ]
Juan Hu [1 ]
Yan Huang [1 ]
Shuang-Wei Ying [1 ]
Xiao-Yan Han [1 ]
Yan-Long Zheng [1 ]
He Huang [1 ]
机构
[1] Bone Marrow Transplantation Centre,The First Affiliated Hospital of Zhejiang University
基金
中国国家自然科学基金;
关键词
D O I
暂无
中图分类号
R581.4 [甲状腺炎]; R733.7 [白血病];
学科分类号
1002 ; 100201 ; 100214 ;
摘要
To the Editor:Sorafenib is a novel,orally available inhibitor of multiple kinases.It has been used in relapsed and refractory FMS-like tyrosine kinase(FLT) -3-positive acute myeloid leukemia(AML) in recent years with favorable outcomes.Thyroiditis and hypothyroidism as side effects have been reported in treatment on renal cell cancer.;Here,we report a case of FLT3-internal tandem duplication(ITD) -positive AML,who developed subacute thyroiditis during treatment with sorafenib.
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页码:2512 / 2513
页数:2
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