Tumor necrosis factor alpha gene-G308A polymorphism associated with bipolar I disorder in the Korean population

被引:33
|
作者
Pae, CU
Lee, KU
Han, H
Serretti, A
Jun, TY [1 ]
机构
[1] Catholic Univ Korea, St Marys Hosp, Coll Med, Dept Psychiat, Seoul, South Korea
[2] Catholic Univ Korea, Coll Med, Dept Microbiol & Immunol, Seoul, South Korea
[3] Univ Vita Salute San Raffaele, Dept Psychiat, Milan, Italy
关键词
-G308A TNF-alpha gene polymorphism; bipolar I disorder; Korea;
D O I
10.1016/j.psychres.2003.06.002
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
We conducted a case-control association study between the -G308A tumor necrosis factor (TNF)-alpha gene polymorphism and 89 patients with bipolar I disorder (BID). A polymerase chain reaction method was used. We found significant differences in genotype and allele distribution. The -G308A TNF-alpha gene polymorphism may confer a risk for BID in the Korean population. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:65 / 68
页数:4
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