Tumor necrosis factor alpha gene-G308A polymorphism associated with bipolar I disorder in the Korean population

被引：33

作者：

Pae, CU

Lee, KU

Han, H

Serretti, A

Jun, TY ^{[1
]}

机构：

[1] Catholic Univ Korea, St Marys Hosp, Coll Med, Dept Psychiat, Seoul, South Korea

[2] Catholic Univ Korea, Coll Med, Dept Microbiol & Immunol, Seoul, South Korea

[3] Univ Vita Salute San Raffaele, Dept Psychiat, Milan, Italy

来源：

PSYCHIATRY RESEARCH | 2004年 / 125卷 / 01期

关键词：

-G308A TNF-alpha gene polymorphism; bipolar I disorder; Korea;

D O I：

10.1016/j.psychres.2003.06.002

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

We conducted a case-control association study between the -G308A tumor necrosis factor (TNF)-alpha gene polymorphism and 89 patients with bipolar I disorder (BID). A polymerase chain reaction method was used. We found significant differences in genotype and allele distribution. The -G308A TNF-alpha gene polymorphism may confer a risk for BID in the Korean population. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

引用

页码：65 / 68

页数：4

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