A case of autoimmune hypophysitis associated with asymptomatic primary biliary cirrhosis

被引：9
|
作者：
Nishiki, M
Murakami, Y
Koshimura, K
Sohmiya, M
Tanaka, J
Yabe, S
Kobayashi, I
Kato, Y
机构：
[1] Shimane Med Univ, Div 1, Dept Med, Izumo, Shimane 6938501, Japan
[2] Gunma Univ, Sch Med, Dept Lab Med, Gunma 3718511, Japan
[3] Gunma Univ, Sch Med, Clin Lab Ctr, Gunma 3718511, Japan
来源：
ENDOCRINE JOURNAL | 1998年 / 45卷 / 05期
关键词：
anti-pituitary antibody; anti-mitochondrial antibody; asymptomatic primary biliary cirrhosis; hypopituitarism;
D O I：
10.1507/endocrj.45.697
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a 61-year old male patient with panhypopituitarism complicated with asymptomatic primary biliary cirrhosis (PBC). T1-weighted magnetic resonance imaging demonstrated high intensity of the anterior pituitary gland. There was no mass lesion or enlargement of the pituitary gland or the stalk. Immunoblot analysis of the patient's sera with rat pituitary antigens revealed a band with a molecular size of 22 kD. Anti-M-2 mitochondrial antibody has been consistently positive far five years. Liver biopsy revealed portal hepatitis with periportal infiltration of the inflammatory cells. This is the first case report of autoimmune hypophysitis complicated with asymptomatic PBC.
引用
收藏
页码：697 / 700
页数：4
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