机构:
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Howard Hughes Med Inst, Boston, MA 02114 USAHarvard Univ, Sch Med, Massachusetts Gen Hosp, Howard Hughes Med Inst, Boston, MA 02114 USA
Masland, RH
[1
]
机构:
[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Howard Hughes Med Inst, Boston, MA 02114 USA
Starburst amacrine cells release two classical neurotransmitters, ACh and GABA. In a tour de force of paired-cell recording, Zheng et al. now show that the starburst cells are mutually excitatory during early development but mutually inhibitory in adult animals. The change occurs by remodeling of both the cholinergic and the GABAergic synapses between starburst cells. The finding gives a precise mechanistic basis for the developmental waves of activity in the retina.
机构:
Univ Utah, Ophthalmol & Visual Sci, Salt Lake City, UT USAUniv Utah, Ophthalmol & Visual Sci, Salt Lake City, UT USA
Tian, Ning
He, Tao
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Univ Utah, Ophthalmol & Visual Sci, Salt Lake City, UT USA
Wuhan Univ, Ophthalmol, Wuhan, Hubei, Peoples R ChinaUniv Utah, Ophthalmol & Visual Sci, Salt Lake City, UT USA
He, Tao
Mortensen, Xavier
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Univ Utah, Ophthalmol & Visual Sci, Salt Lake City, UT USAUniv Utah, Ophthalmol & Visual Sci, Salt Lake City, UT USA
Mortensen, Xavier
Wang, Ping
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机构:
Univ Utah, Ophthalmol & Visual Sci, Salt Lake City, UT USAUniv Utah, Ophthalmol & Visual Sci, Salt Lake City, UT USA
机构:
Univ Arkansas Med Sci, Physiol, Little Rock, AR 72205 USAUniv Arkansas Med Sci, Physiol, Little Rock, AR 72205 USA
Kim, K.
Zhou, Z. J.
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Univ Arkansas Med Sci, Physiol, Little Rock, AR 72205 USA
Yale Univ, Sch Med, Ophthalmol & Visual Sci, New Haven, CT USAUniv Arkansas Med Sci, Physiol, Little Rock, AR 72205 USA