The many roles of starburst amacrine cells

被引:31
|
作者
Masland, RH [1 ]
机构
[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Howard Hughes Med Inst, Boston, MA 02114 USA
关键词
D O I
10.1016/j.tins.2005.06.002
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Starburst amacrine cells release two classical neurotransmitters, ACh and GABA. In a tour de force of paired-cell recording, Zheng et al. now show that the starburst cells are mutually excitatory during early development but mutually inhibitory in adult animals. The change occurs by remodeling of both the cholinergic and the GABAergic synapses between starburst cells. The finding gives a precise mechanistic basis for the developmental waves of activity in the retina.
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页码:395 / 396
页数:2
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