A convenient method for the preparation of 5-, 6- and 7-azaindoles and their derivatives

被引：0
|
作者：
Hands, D
Bishop, B
Cameron, M
Edwards, JS
Cottrell, IF
Wright, SHB
机构：
来源：
SYNTHESIS-STUTTGART | 1996年 / 07期
关键词：
directed ortho metallation; 3-substituted-2-amino-pyridines; 5-; 6-; and; 7-azaindoles;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The directed ortho lithiation of 2-tert-butoxycarbonylamino-3-methylpyridine (6 a) has provided a convenient method for the preparation of 1H-pyrrolo[2,3-b]pyridine (4 a, 7-azaindole). This procedure has been used to prepare a range of 3-substituted 2-tert-butoxycarbonylaminopyridines 6, 2- and 3-substituted and 2,3-disubstituted 1H-pyrrolo[2,3-b]pyridines 4 and shown to be of value in the preparation of 1H-pyrrolo[3,2-c]pyridine (15, 5-azaindole) and 1H-pyrrolo[2,3-c]pyridine (18, 6-azaindole) and derivatives.
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页码：877 / &
页数：7
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