Molecular structure of tight junctions and their role in epithelial transport

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作者
Anderson, JM [1 ]
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[1] Yale Univ, Sch Med, New Haven, CT 06520 USA
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Q4 [生理学];
学科分类号
071003 ;
摘要
Tight junctions create a paracellular barrier with physiological properties that differ among epithelia. Among these differences are electrical resistance and discrimination for solute size and charge. Emerging evidence suggests that a large family of transmembrane proteins called the claudins create these variable properties.
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页码:126 / 130
页数:5
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