Application of Physiologically Based Pharmacokinetic (PBPK) Modeling to Predict Desloratadine Pharmacokinetics in Children

被引:0
|
作者
Zhou, W. [1 ]
Johnson, T. [2 ]
Bui, K. [1 ]
Cheung, S. Y. A. [3 ]
Li, J. [1 ]
Xu, H. [1 ]
Al-Huniti, N. [1 ]
Zhou, D. [1 ]
机构
[1] AstraZeneca, Waltham, MA USA
[2] Simcyp, Sheffield, S Yorkshire, England
[3] AstraZeneca, Cambridge, England
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
W-090
引用
收藏
页码:S138 / S138
页数:1
相关论文
共 50 条
  • [21] A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancer
    Cheeti, Sravanthi
    Budha, Nageshwar R.
    Rajan, Sharmila
    Dresser, Mark J.
    Jin, Jin Y.
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2013, 34 (03) : 141 - 154
  • [22] Physiologically-Based Pharmacokinetic (PBPK) Modeling of Buprenorphine in Adults, Children and Preterm Neonates
    Kovar, Lukas
    Schraepel, Christina
    Selzer, Dominik
    Kohl, Yvonne
    Bals, Robert
    Schwab, Matthias
    Lehr, Thorsten
    PHARMACEUTICS, 2020, 12 (06) : 1 - 22
  • [23] Application of Physiologically Based Pharmacokinetic (PBPK) Modeling to Support Dose Selection: Report of an FDA Public Workshop on PBPK
    Wagner, C.
    Zhao, P.
    Pan, Y.
    Hsu, V.
    Grillo, J.
    Huang, S. M.
    Sinha, V.
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2015, 4 (04): : 226 - 230
  • [24] Transporter-related physiologically based pharmacokinetic (PBPK) modeling
    Watanabe, Takao
    Kusuhara, Hiroyuki
    Maeda, Kazuya
    Sugiyama, Yuichi
    DRUG METABOLISM REVIEWS, 2006, 38 : 215 - 215
  • [25] Physiologically-based pharmacokinetic modeling to predict the clinical pharmacokinetics of monoclonal antibodies
    Glassman, Patrick M.
    Balthasar, Joseph P.
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2016, 43 (04) : 427 - 446
  • [26] Physiologically Based Pharmacokinetic (PBPK) Modeling of Amoxicillin in Neonates and Infants
    Lukacova, Viera
    Bolger, Michael B.
    Woltosz, Walter S.
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2013, 40 : S124 - S125
  • [27] Physiologically based pharmacokinetic (PBPK) modeling of disposition of epiroprim in humans
    Luttringer, O
    Theil, FP
    Poulin, P
    Schmitt-Hoffmann, AH
    Guentert, TW
    Lavé, T
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2003, 92 (10) : 1990 - 2007
  • [28] Physiologically based pharmacokinetic (PBPK) modeling of genistein in rats.
    Schlosser, PM
    Borghoff, SJ
    Coldham, NG
    Tran, HT
    Upmeier, A
    Zager, MG
    TOXICOLOGICAL SCIENCES, 2003, 72 : 180 - 180
  • [29] Physiologically-based pharmacokinetic modeling to predict the clinical pharmacokinetics of monoclonal antibodies
    Patrick M. Glassman
    Joseph P. Balthasar
    Journal of Pharmacokinetics and Pharmacodynamics, 2016, 43 : 427 - 446
  • [30] Physiologically Based Pharmacokinetic (PBPK) Modeling for Betrixaban and the Impact of P-Glycoprotein Inhibition on Betrixaban Pharmacokinetics
    Leeds, Janet M.
    Ke, Alice
    Yeo, Karen Rowland
    Curnutte, John T.
    Conley, Pamela B.
    BLOOD, 2017, 130