The association of serotype and pulsed-field gel electrophoresis genotype in isolates of Streptococcus pneumoniae isolated in Israel

被引：2
|
作者：
Bar-Meir, M. [1 ,2 ]
Naaman, G. [3 ]
Assous, M. [4 ]
Korenman, Z. [5 ]
Valinsky, L. [5 ]
Picard, E. [2 ,6 ]
机构：
[1] Shaare Zedek Med Ctr, Infect Dis, IL-91031 Jerusalem, Israel
[2] Hebrew Univ Jerusalem, Fac Med, Jerusalem, Israel
[3] Shaare Zedek Med Ctr, Pediat, IL-91031 Jerusalem, Israel
[4] Shaare Zedek Med Ctr, Microbiol Lab, IL-91031 Jerusalem, Israel
[5] Minist Hlth, Cent Labs, Jerusalem, Israel
[6] Shaare Zedek Med Ctr, Pediat Pulmonol, IL-91031 Jerusalem, Israel
来源：
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2015年 / 34卷
关键词：
S; pneumoniae; Pulsed-field; Gel; Electrophoresis; Genotype; Serotype; EVOLUTION; DISEASE; CLONE;
D O I：
10.1016/j.ijid.2015.02.023
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The relationship between Streptococcus pneumoniae isolates causing invasive infections in children admitted to a single center in central Israel was examined by pulsed-field gel electrophoresis (PFGE) and serotyping. Although there was a close correlation between serotype and PFGE clone, the genetic diversity varied by serotype, with some genotypes comprising multiple serotypes. Additionally, clones C and D were associated with higher penicillin minimum inhibitory concentrations. Serotyping alone may be insufficient for epidemiological mapping of pneumococcal isolates in the era of pneumococcal conjugate polysaccharide vaccines. (C) 2015 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
引用
收藏
页码：38 / 40
页数：3
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