Bickerstaff's brainstem encephalitis after an outbreak of Campylobacter jejuni enteritis

被引：9

作者：

Mori, Masahiro ^{[1
]}

Koga, Michiaki ^{[2
]}

Yuki, Nobuhiro ^{[2
]}

Hattori, Takamichi ^{[1
]}

Kuwabara, Satoshi ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Med, Dept Neurol, Chuo Ku, Chiba 2608670, Japan

[2] Dokkyo Med Univ, Dept Neurol, Tochigi 3210293, Japan

来源：

JOURNAL OF NEUROIMMUNOLOGY | 2008年 / 196卷 / 1-2期

关键词：

anti-ganglioside antibody; Bickerstaff's brainstem encephalitis; Campylobacter jejuni;

D O I：

10.1016/j.jneuroim.2008.02.011

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Twenty-eight patients suffered Campylobacter jejuni enteritis after eating raw chicken. Among them, only one patient developed Bickerstaff's brainstem encephalitis, who carried anti-GQ1b IgG antibodies. In contrast, none of the others did the autoantibodies. C. jejuni was cultured from all stool samples from five patients with enteritis alone. All the isolates had the same genotype, cst-II (Asn51), which are characteristic of strains isolated from Bickerstaff's brainstem encephalitis. These findings suggest that host susceptibility may play a role in inducing the production of anti-ganglioside antibodies and the development of Bickerstaff's brainstem encephalitis. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：143 / 146

页数：4

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