Chip-based Microelectrodes for detection of single-nucleotide mismatch

被引：28
|
作者：
Li, XH
Zhou, YL
Sutherland, TC
Baker, B
Lee, JS
Kraatz, HB
机构：
[1] Univ Saskatchewan, Dept Biochem, Saskatoon, SK S7N 5E5, Canada
[2] Univ Saskatchewan, Dept Chem, Saskatoon, SK S7N 5C9, Canada
[3] Univ Utah, Dept Engn, Microfabricat Lab, Salt Lake City, UT 84112 USA
来源：
ANALYTICAL CHEMISTRY | 2005年 / 77卷 / 17期
关键词：
D O I：
10.1021/ac050741o
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Microelectrode arrays having eight 10-mu m-diameter gold microelectrodes arranged on a gold-covered Si chip were designed and characterized. The chips prove useful for the detection of single-nucleotide mismatches in unlabeled and prehybridized DNA by electrochemical impedance spectroscopy.
引用
收藏
页码：5766 / 5769
页数：4
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