concentration inequality;
genomics;
random matrix;
Schatten norm;
REGULARIZATION;
ESTIMATORS;
D O I:
10.1002/sta4.316
中图分类号:
O21 [概率论与数理统计];
C8 [统计学];
学科分类号:
020208 ;
070103 ;
0714 ;
摘要:
For high-dimensional data, the standard empirical estimator for the covariance matrix is very poor, and thus many methods have been proposed to more accurately estimate the covariance structure of high-dimensional data. In this article, we consider estimation under the assumption of sparsity but regularize with respect to the individual false-positive rate for incorrectly including a matrix entry in the support of the final estimator. The two benefits of this approach are (1) an interpretable regularization parameter removing the need for computationally expensive tuning and (2) extremely fast computation time arising from use of a binary search algorithm implemented to find the best estimator within a carefully constructed operator norm ball. We compare our approach to universal thresholding estimators and lasso-style penalized estimators on both simulated data and data from gene expression for cancerous tumours.
机构:
MIT, Sloan Sch Management, 30 Mem Dr, Cambridge, MA 02142 USAMIT, Sloan Sch Management, 30 Mem Dr, Cambridge, MA 02142 USA
Avella-Medina, Marco
Battey, Heather S.
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h-index: 0
机构:
Imperial Coll London, Dept Math, 545 Huxley Bldg,South Kensington Campus, London SW7 2AZ, EnglandMIT, Sloan Sch Management, 30 Mem Dr, Cambridge, MA 02142 USA
Battey, Heather S.
Fan, Jianqing
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机构:
Princeton Univ, Dept Operat Res & Financial Engn, 205 Sherred Hall, Princeton, NJ 08540 USAMIT, Sloan Sch Management, 30 Mem Dr, Cambridge, MA 02142 USA
Fan, Jianqing
Li, Quefeng
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机构:
Univ N Carolina, Dept Biostat, 3105D McGavran Greenberg Hall, Chapel Hill, NC 27599 USAMIT, Sloan Sch Management, 30 Mem Dr, Cambridge, MA 02142 USA
机构:
Iowa State Univ, Dept Stat, Ames, IA 50011 USAIowa State Univ, Dept Stat, Ames, IA 50011 USA
Li, Jun
Chen, Song Xi
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h-index: 0
机构:
Iowa State Univ, Dept Stat, Ames, IA 50011 USA
Peking Univ, Guanghua Sch Management, Beijing 100871, Peoples R China
Peking Univ, Ctr Stat Sci, Beijing 100871, Peoples R ChinaIowa State Univ, Dept Stat, Ames, IA 50011 USA
机构:
School of Computer and Data Engineering, NingboTech University, Ningbo
College of Mathematics, Sichuan University, ChengduSchool of Computer and Data Engineering, NingboTech University, Ningbo
机构:
Beijing Normal Univ, Ctr Stat & Data Sci, Zhuhai 519087, Peoples R ChinaBeijing Normal Univ, Ctr Stat & Data Sci, Zhuhai 519087, Peoples R China
Wang, Xiaoyi
Xu, Gongjun
论文数: 0引用数: 0
h-index: 0
机构:
Univ Michigan, Dept Stat, Ann Arbor, MI 48109 USABeijing Normal Univ, Ctr Stat & Data Sci, Zhuhai 519087, Peoples R China
Xu, Gongjun
Zheng, Shurong
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h-index: 0
机构:
Northeast Normal Univ, Sch Math & Stat, Changchun 130024, Jilin, Peoples R China
Northeast Normal Univ, KLAS, Changchun 130024, Jilin, Peoples R ChinaBeijing Normal Univ, Ctr Stat & Data Sci, Zhuhai 519087, Peoples R China