HIV-1 Drug Resistance Mutations Among Antiretroviral-Naive HIV-1-Infected Patients in Asia: Results From the TREAT Asia Studies to Evaluate Resistance-Monitoring Study

被引：40

作者：

Sungkanuparph, Somnuek ^{[1
]}

Oyomopito, Rebecca ^{[7
]}

Sirivichayakul, Sunee ^{[2
,3
]}

Sirisanthana, Thira ^{[5
]}

Li, Patrick C. K. ^{[8
]}

Kantipong, Pacharee ^{[6
]}

Lee, Christopher K. C. ^{[9
]}

Kamarulzaman, Adeeba ^{[10
]}

Messerschmidt, Liesl ^{[4
]}

Law, Matthew G. ^{[7
]}

Phanuphak, Praphan ^{[2
,3
]}

机构：

[1] Mahidol Univ, Ramathibodi Hosp, Fac Med, Bangkok 10400, Thailand

[2] Chulalongkorn Univ, HIV NAT Thai Red Cross AIDS Res Ctr, Bangkok 10330, Thailand

[3] Chulalongkorn Univ, Fac Med, Bangkok 10330, Thailand

[4] TREAT Asia, Fdn AIDS Res, Bangkok, Thailand

[5] Res Inst Hlth Sci, Chiang Mai, Thailand

[6] Chiang Rai Reg Hosp, Chiang Rai, Thailand

[7] Univ New S Wales, Natl Ctr HIV Epidemiol & Clin Res, Sydney, NSW, Australia

[8] Queen Elizabeth Hosp, Hong Kong, Hong Kong, Peoples R China

[9] Hosp Sungai Buloh, Sungai Buloh, Malaysia

[10] Univ Malaya, Kuala Lumpur, Malaysia

来源：

CLINICAL INFECTIOUS DISEASES | 2011年 / 52卷 / 08期

关键词：

REVERSE-TRANSCRIPTASE; INFECTED PATIENTS; GENOTYPIC RESISTANCE; THRESHOLD SURVEY; DUAL-NUCLEOSIDE; THERAPY; PREVALENCE; ZIDOVUDINE; SURVIVAL; STRAINS;

D O I：

10.1093/cid/cir107

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Of 682 antiretroviral-naive patients initiating antiretroviral therapy in a prospective, multicenter human immunodeficiency virus type 1 (HIV-1) drug resistance monitoring study involving 8 sites in Hong Kong, Malaysia, and Thailand, the prevalence of patients with >= 1 drug resistance mutation was 13.8%. Primary HIV drug resistance is emerging after rapid scaling-up of antiretroviral therapy use in Asia.

引用

页码：1053 / 1057

页数：5

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