Pyridylcarbene formation by thermal decomposition of 7-bromo-3-methyl-[1,2,3] triazolo[ 1,5-a] pyridine under pressure

被引：8
|
作者：
Abarca, Belen [1 ]
Ballesteros, Rafael [1 ]
Blanco, Fernando [1 ]
机构：
[1] Univ Valencia, Fac Farm, Dept Quim Organ, Avda Vicente Andres Estelles S-N, Valencia 46100, Spain
来源：
ARKIVOC | 2007年
关键词：
pyridylcarbene; high pressure reaction; triazolopyridines decomposition;
D O I：
10.3998/ark.5550190.0008.426
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
7-Bromo-3-methyl-[1,2,3]triazolo[1,5- a] pyridine 1 at 1.7 atm and 100 degrees C decompose to form a pyridylcarbene intermediate by nitrogen expulsion. The carbene stabilization give 2-bromo-6-vinylpyridine 2, 1-(6-bromopyridin-2-yl) ethanol 3, 1-(6-Bromopyridin-2-yl) ethanone 4, 2bromo- 6-[ 2-( 6- bromopyridin- 2- yl)- 2- methyl- trans- cyclopropyl] pyridine 5, and 2- bromo- 6-[ 2-( 6bromopyridin-2-yl)-2-methyl-cis-cyclopropyl] pyridine 6.
引用
收藏
页码：297 / 303
页数：7
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