Endothelins and their receptors as biological markers for oral cancer

被引：13
|
作者：
Hoffmann, Renata R.
Yurgel, Liliane S. [2 ]
Campos, Maria M. [1 ,3 ]
机构：
[1] Pontificia Univ Catolica Rio Grande do Sul, Sch Dent, Postgrad Program Dent Coll, BR-90619900 Porto Alegre, RS, Brazil
[2] Pontificia Univ Catolica Rio Grande do Sul, Hosp Sao Lucas, Stomatol Serv, BR-90619900 Porto Alegre, RS, Brazil
[3] Pontificia Univ Catolica Rio Grande do Sul, Inst Toxicol, BR-90619900 Porto Alegre, RS, Brazil
来源：
ORAL ONCOLOGY | 2010年 / 46卷 / 09期
关键词：
Oral cancer; Endothelin-1; Endothelin receptors; Prognostic factor; TEA POLYPHENOL EPIGALLOCATECHIN-3-GALLATE; SIGNALING PATHWAYS; CARCINOMA-CELLS; EMERGING ROLE; AXIS; ANTAGONISM; EXPRESSION; PEPTIDE; LUNG; DIAGNOSIS;
D O I：
10.1016/j.oraloncology.2010.06.015
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Oral squamous cell carcinoma (OSCC) is one of the most common malignancies recognized nowadays, and represents a public health problem. Its early detection is the better alternative to provide a good quality of life for the patients. During the last years, several studies have identified potential biomarkers of OSCC progression and prognosis. Endothelins and their receptors are involved in several pathophysiological conditions and in various cancer types. The present review article discusses whether the endothelin system would represent a biomarker for OSCC. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：644 / 647
页数：4
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