Multicenter, randomized phase II study of neoadjuvant pembrolizumab plus chemotherapy and chemoradiotherapy in esophageal adenocarcinoma (EAC).

被引:13
|
作者
Shah, Manish A.
Almhanna, Khaldoun
Iqbal, Syma
Thakkar, Prashant
Schneider, Bryan J.
Yantiss, Rhonda
Wu, Yiru
Futamura, Emma
Port, Jeffrey L.
Spinelli, Cathy
Sarkar, Sandipto
Christos, Paul J.
Brar, Gagandeep
Betel, Doron
Sanfilippo, Nicholas J.
Altorki, Nasser K.
机构
[1] Weill Cornell Med, New York, NY USA
[2] Lifespan, Providence, RI USA
[3] USC Norris Comprehens Canc Ctr, Los Angeles, CA USA
[4] Weill Cornell Med Coll, New York Presbyterian Hosp, New York, NY USA
[5] Weill Cornell Med, New York, NY USA
[6] Weill Cornell, New York, NY USA
[7] Lifespan Canc Inst, Providence, RI USA
[8] Cornell Univ, Weill Med Coll, New York, NY USA
[9] Weill Cornell Med Coll, New York, NY USA
[10] Weill Cornell Med Coll, Dept Biostat & Epidemiol, New York, NY USA
关键词
D O I
10.1200/JCO.2021.39.15_suppl.4005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4005
引用
收藏
页数:2
相关论文
共 50 条
  • [11] A phase II study of perioperative mFOLFOX chemotherapy plus pembrolizumab combination in patients with potentially resectable adenocarcinoma of the esophageal, gastroesophageal junction (GEJ), and stomach
    Sun, Weijing
    Saeed, Anwaar
    Al-Rajabi, Raed Moh'd Taiseer
    Kasi, Anup
    Veeramachaneni, Nirmal K.
    Al-Kasspooles, Mazin Mazin
    Baranda, Joaquina Celebre
    Phadnis, Milind
    Godwin, Andrew K.
    Olyaee, Mojtaba
    Madan, Rashna
    Nagji, Alykhan
    Williamson, Stephen K.
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (04)
  • [12] Effects of neoadjuvant chemotherapy plus chemoradiotherapy on lymph nodes in rectal adenocarcinoma
    Chotard, Guillaume
    Capdepont, Maylis
    Denost, Quentin
    Smith, Denis
    Vendrely, Veronique
    Rullier, Eric
    Rullier, Anne
    VIRCHOWS ARCHIV, 2021, 479 (04) : 657 - 666
  • [13] Effects of neoadjuvant chemotherapy plus chemoradiotherapy on lymph nodes in rectal adenocarcinoma
    Guillaume Chotard
    Maylis Capdepont
    Quentin Denost
    Denis Smith
    Véronique Vendrely
    Eric Rullier
    Anne Rullier
    Virchows Archiv, 2021, 479 : 657 - 666
  • [14] Preliminary results from the multicenter, randomized phase III trial (SCIENCE): Comparing chemotherapy plus sintilimab and chemoradiotherapy plus sintilimab versus chemoradiotherapy for neoadjuvant treatment in resectable locally advanced esophageal squamous cell carcinoma.
    Leng, Xuefeng
    He, Wenwu
    Lyu, Jiahua
    Gong, Lei
    Hu, Tongchen
    Zhou, Haining
    Peng, Lin
    Liu, Guangyuan
    Wang, Kangning
    Fang, Qiang
    Qi, Yunxiang
    Zhou, Yehan
    Zhang, Wencheng
    Tang, Peng
    Li, Tao
    Han, Yongtao
    JOURNAL OF CLINICAL ONCOLOGY, 2025, 43 (4_SUPPL) : LBA329 - LBA329
  • [15] Preoperative Concurrent Chemoradiotherapy Versus Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer: Phase II Randomized Study
    Wang, Xin
    Zhao, Dong-Bing
    Yang, Lin
    Chi, Yihebali
    Zhao, Hong
    Jiang, Li-Ming
    Jiang, Jun
    Tang, Yuan
    Li, Ning
    Liu, Wen-Yang
    Dou, Li-Zhou
    Zou, Shuang-Mei
    Xue, Li-Yan
    Ren, Jian-Song
    Tian, Yan-Tao
    Che, Xu
    Guo, Chun-Guang
    Bai, Xiao-Feng
    Sun, Yue-Min
    Wang, Shu-Lian
    Song, Yong-Wen
    Liu, Yue-Ping
    Fang, Hui
    Li, Ye-Xiong
    Jin, Jing
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [16] Induction Chemotherapy Plus Neoadjuvant Chemoradiation for Esophageal and Gastroesophageal Junction Adenocarcinoma
    Ho, Felix
    Torphy, Robert J.
    Friedman, Chloe
    Leong, Stephen
    Kim, Sunnie
    Wani, Sachin
    Schefter, Tracey
    Scott, Christopher D.
    Mitchell, John D.
    Weyant, Michael J.
    Meguid, Robert A.
    Gleisner, Ana L.
    Goodman, Karyn A.
    McCarter, Martin D.
    ANNALS OF SURGICAL ONCOLOGY, 2021, 28 (12) : 7208 - 7218
  • [17] Induction Chemotherapy Plus Neoadjuvant Chemoradiation for Esophageal and Gastroesophageal Junction Adenocarcinoma
    Felix Ho
    Robert J. Torphy
    Chloe Friedman
    Stephen Leong
    Sunnie Kim
    Sachin Wani
    Tracey Schefter
    Christopher D. Scott
    John D. Mitchell
    Michael J. Weyant
    Robert A. Meguid
    Ana L. Gleisner
    Karyn A. Goodman
    Martin D. McCarter
    Annals of Surgical Oncology, 2021, 28 : 7208 - 7218
  • [18] Phase II randomized multicentre study comparing neoadjuvant chemoradiotherapy followed by consolidation chemotherapy to neoadjuvant chemoradiotherapy alone in non-metastatic rectal cancer patients
    Elsamany, S. A.
    Aljubran, A.
    El-Khatib, H. M. A.
    Elmorsy, S.
    Hassanin, F.
    Alsuhaibani, A.
    Tashkandy, E.
    Abdelkhalek, S.
    Algarni, M.
    Alzahrani, S.
    Yousef, M.
    Ahmad, M. Shouki
    Bazarbashi, A.
    ANNALS OF ONCOLOGY, 2024, 35 : S105 - S105
  • [19] Multicenter phase II study of neoadjuvant nivolumab or nivolumab plus relatlimab (anti-LAG3 antibody) plus chemoradiotherapy in stage II/III esophageal/gastroesophageal junction (E/GEJ) carcinoma
    Kelly, Ronan Joseph
    Zaidi, Ali Hussainy
    Canzoniero, Jenna VanLiere
    Feliciano, Josephine Louella
    Hales, Russell K.
    Voong, K. Ranh
    Battafarano, Richard James
    Jobe, Blair Anderson
    Yang, Stephen
    Broderick, Stephen
    Ha, Jinny Suk
    Smith, Kellie Nicole
    Thompson, Elizabeth D.
    Shaikh, Fyza
    Shin, Eun Ji
    Amjad, Ali Imran
    Guerrieri, Patrizia
    Hu, Chen
    Anagnostou, Valsamo
    Lam, Vincent K.
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (04)
  • [20] Neoadjuvant Toripalimab plus Concurrent Chemoradiotherapy in the Locally Advanced Adenocarcinoma of Esophagogastric Junction: A Phase II Trial
    Du, R.
    Geng, J.
    Liu, Z.
    Sui, X.
    Li, S.
    Tang, L.
    Wang, Z.
    Zhang, X.
    Yan, Y.
    Wu, A.
    Li, Z.
    Li, Y.
    Wang, W.
    Li, Z.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2024, 120 (02): : S48 - S48