Synthesis and antimicrobial evaluation of some novel dithiolane, thiophene, coumarin, and 2-pyridone derivatives

被引：19
|
作者：
Mahmoud, Mahmoud R. [1 ]
Abu El-Azm, Fatma S. M. [1 ]
Ali, Amira T. [1 ]
Ali, Yasmeen M. [1 ]
机构：
[1] Ain Shams Univ, Fac Sci, Dept Chem, Cairo 11566, Egypt
来源：
SYNTHETIC COMMUNICATIONS | 2017年 / 47卷 / 17期
关键词：
Cyanoacetohydrazide; dithiolane derivatives; hydrazide-hydrazone; thiophene derivatives; STRUCTURE-BASED DESIGN; BIOLOGICAL EVALUATION; 2-PYRIDONE-CONTAINING PEPTIDOMIMETICS; AGENTS; INHIBITORS; 1,3,4-THIADIAZOLES; NAPHTHALENE; HYDRAZONES; SPECTRA; ANALOGS;
D O I：
10.1080/00397911.2017.1336776
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Novel 2-cyano-N-[1-(naphtha-2-yl) ethylidene] acetohydrazide 1 was utilized as key intermediate for the synthesis of some new dithiolane, thiophene, coumarin, 2-pyridone, and other related products containing a hydrazide moiety. Newly synthesized compounds were characterized by elemental analyses and spectral data (IR, H-1 NMR and mass spectra). The antimicrobial activity of the synthesized compounds was evaluated.
引用
收藏
页码：1591 / 1600
页数：10
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