Heparin induced thrombocytopenia thrombosis (HIT/T) is associated with a high morbidity and mortality. Diagnosis is essentially clinical and negative results of laboratory assays do not exclude the diagnosis. Treatment involves stopping all heparin immediately and giving an alternative thrombin inhibitor. The adoption of low molecular weight heparins is one reason for the reduced incidence of this disease in recent years.
机构:
Oregon Hlth & Sci Univ, Dept Pediat, Div Hematol Oncol, 3181 Sw Sam Jackson Pk Rd, Portland, OR 97201 USAOregon Hlth & Sci Univ, Dept Pediat, Div Hematol Oncol, 3181 Sw Sam Jackson Pk Rd, Portland, OR 97201 USA
Hogan, Marie
Berger, Jeffrey S.
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NYU, Sch Med, Dept Med, Div Cardiol & Hematol, 530 First Ave,SKI 9R, New York, NY 10016 USAOregon Hlth & Sci Univ, Dept Pediat, Div Hematol Oncol, 3181 Sw Sam Jackson Pk Rd, Portland, OR 97201 USA