Heparin induced thrombocytopenia thrombosis (HIT/T) syndrome: diagnosis and treatment

被引:48
|
作者
Baglin, TP [1 ]
机构
[1] Addenbrookes NHS Trust, Dept Haematol, Cambridge CB2 2QQ, England
关键词
heparin induced thrombocytopenia; thrombosis; immune complexes; platelet aggregating factor;
D O I
10.1136/jcp.54.4.272
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Heparin induced thrombocytopenia thrombosis (HIT/T) is associated with a high morbidity and mortality. Diagnosis is essentially clinical and negative results of laboratory assays do not exclude the diagnosis. Treatment involves stopping all heparin immediately and giving an alternative thrombin inhibitor. The adoption of low molecular weight heparins is one reason for the reduced incidence of this disease in recent years.
引用
收藏
页码:272 / 274
页数:3
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