A Phase II Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Obinutuzumab or Placebo in Combination with Mycophenolate Mofetil in Patients with Active Class III or IV Lupus Nephritis

被引：0
|
作者：
Furie, Richard [1 ]
Aroca, Gustavo [2 ,3 ]
Alvarez, Analia [4 ]
Fragoso-Loyo, Hilda [5 ]
Zuta Santillan, Elizabeth [6 ]
Rovin, Brad [7 ]
Schindler, Thomas [8 ]
Hassan, Imran [9 ]
Cascino, Matthew [10 ]
Garg, Jay P. [11 ]
Malvar, Ana [12 ]
机构：
[1] Northwell Hlth, Great Neck, NY USA
[2] Simon Bolivar Univ, Barranquilla, Colombia
[3] Clin Costa, Barranquilla, Colombia
[4] CEMIC, Buenos Aires, DF, Argentina
[5] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Immunol & Rheumatol, Mexico City, DF, Mexico
[6] Inst Ginecol & Reprod, Lima, Peru
[7] Ohio State Univ, Med Ctr, Columbus, OH 43210 USA
[8] F Hoffmann La Roche & Cie AG, Basel, Switzerland
[9] Hoffmann La Roche Ltd, Mississauga, ON, Canada
[10] Genentech Inc, San Francisco, CA USA
[11] Genentech Inc, San Francisco, CA 94080 USA
[12] Hosp Fernandez, Org Maed Invest, Buenos Aires, DF, Argentina
来源：
ARTHRITIS & RHEUMATOLOGY | 2019年 / 71卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
0939
引用
收藏
页数：3
相关论文
共 50 条
  • [21] Journal Club: Efficacy and Safety of Voclosporin Versus Placebo for Lupus Nephritis (AURORA 1): A Double-Blind, Randomized, Multicenter, Placebo-Controlled, Phase 3 Trial
    Rubio, Jose
    Kyttaris, Vasileios
    ACR OPEN RHEUMATOLOGY, 2021, 3 (12) : 827 - 831
  • [22] A Randomized, Double-Blind, Placebo-Controlled Phase 2a Study of Tildrakizumab Efficacy and Safety in Patients With Active Ankylosing Spondylitis
    Peters, Eric
    Chou, Richard C.
    Rozzo, Stephen J.
    Yao, Siu-Long
    Fructuoso, Ferran Jose Garcia
    JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2023, 29 (05) : 223 - 229
  • [23] THE SAFETY AND TOLERABILITY OF LACOSAMIDE IN RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE II/III CLINICAL TRIALS
    Gil-Nagel, A.
    Biton, V.
    Fountain, N.
    Rosenow, F.
    Hebert, D.
    Doty, P.
    EPILEPSIA, 2009, 50 : 110 - 110
  • [24] Efficacy and safety of ustekinumab in Japanese patients with severe atopic dermatitis: a randomized, double-blind, placebo-controlled, phase II study
    Saeki, H.
    Kabashima, K.
    Tokura, Y.
    Murata, Y.
    Shiraishi, A.
    Tamamura, R.
    Randazzo, B.
    Imanaka, K.
    BRITISH JOURNAL OF DERMATOLOGY, 2017, 177 (02) : 419 - 427
  • [25] A double-blind, placebo-controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome
    Nyhlin, H
    Bang, C
    Elsborg, L
    Silvennoinen, J
    Holme, I
    Rüegg, P
    Jones, J
    Wagner, A
    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2004, 39 (02) : 119 - 126
  • [26] A double-blind, randomized, placebo-controlled, parallel study to evaluate the efficacy and safety of imidafenacin in patients with overactive bladder in Taiwan
    Chuang, Yao-Chi
    Lin, Chih-Chieh
    Chow, Po-Ming
    Lien, Chi-Shun
    Tsui, Ke-Hung
    Chou, Chieh-Lung
    Lee, Hsiang-Ying
    Meng, En
    Kuo, Hann-Chorng
    LUTS-LOWER URINARY TRACT SYMPTOMS, 2021, 13 (01) : 108 - 117
  • [27] CETACAINE EFFICACY - A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY
    LACHTER, J
    JACOBS, R
    LAVY, A
    SUISSA, A
    WEISLER, A
    EIDELMAN, S
    GASTROENTEROLOGY, 1988, 94 (05) : A245 - A245
  • [28] A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of RM-131 in Patients with Diabetic Gastroparesis
    Lembo, Anthony
    Camilleri, Michael
    McCallum, Richard W.
    Sastre, Ramon F.
    Breton, Cristian F.
    Spence, Sharon C.
    White, Jeffery
    Gottesdiener, Keith
    Stoner, Elizabeth
    GASTROENTEROLOGY, 2014, 146 (05) : S158 - S159
  • [29] Efficacy and Safety of Golimumab in Patients With Ankylosing Spondylitis Results of a Randomized, Double-Blind, Placebo-Controlled, Phase III Trial
    Inman, Robert D.
    Davis, John C., Jr.
    van der Heijde, Desiree
    Dickman, Laura
    Sieper, Joachim
    Kim, Sung Il
    Mack, Michael
    Han, John
    Visvanathan, Sudha
    Xu, Zhenhua
    Su, Benjamin
    Beutler, Anna
    Braun, Juergen
    ARTHRITIS AND RHEUMATISM, 2008, 58 (11): : 3402 - 3412
  • [30] A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of a bupivacaine hydrochloride implant in patients undergoing abdominoplasty
    Beaton, Alina C.
    Solanki, Daneshvari
    Salazar, Hernan
    Folkerth, Steve
    Singla, Neil
    Minkowitz, Harold S.
    Leiman, David
    Vaughn, Ben
    Skuban, Nina
    Niebler, Gwendolyn
    REGIONAL ANESTHESIA AND PAIN MEDICINE, 2023, 48 (12) : 601 - 607
12345