Endometriosis-associated pain (EAP) has a significant impact on the quality of life of those affected and their families. Recognizing that endometriosis is a chronic condition associated with an impairment in function and negative social impact, there is a shift toward reducing diagnostic delays and initiating timely management. This article provides a comprehensive and practical approach to the clinical diagnosis of EAP, which can subsequently facilitate prompt and directed treatment. The key components of the history, physical examination, and high-quality imaging to evaluate suspected EAP and related pain conditions are presented. Currently, biomarkers have limited utility in the diagnosis of endometriosis, but research in this area continues; development of a reliable noninvasive test for endometriosis may further improve early identification of this condition. (C) 2019 AAGL. All rights reserved.
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Univ Michigan, Dept Obstet & Gynecol, Ann Arbor, MI 48109 USAUniv Michigan, Dept Obstet & Gynecol, Ann Arbor, MI 48109 USA
As-Sanie, Sawsan
Kim, Jieun
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Massachusetts Gen Hosp, Dept Radiol, Athinoula A Martinos Ctr Biomed Imaging, Charlestown, MA USAUniv Michigan, Dept Obstet & Gynecol, Ann Arbor, MI 48109 USA
Kim, Jieun
Schmidt-Wilcke, Tobias
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Univ Michigan Hlth Syst, Dept Anesthesiol, Chron Pain & Fatigue Res Ctr, Ann Arbor, MI 48109 USAUniv Michigan, Dept Obstet & Gynecol, Ann Arbor, MI 48109 USA
Schmidt-Wilcke, Tobias
Sundgren, Pia C.
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Univ Michigan, Dept Radiol, Ann Arbor, MI 48109 USAUniv Michigan, Dept Obstet & Gynecol, Ann Arbor, MI 48109 USA
Sundgren, Pia C.
Clauw, Daniel J.
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Univ Michigan Hlth Syst, Dept Anesthesiol, Chron Pain & Fatigue Res Ctr, Ann Arbor, MI 48109 USAUniv Michigan, Dept Obstet & Gynecol, Ann Arbor, MI 48109 USA
Clauw, Daniel J.
Napadow, Vitaly
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Massachusetts Gen Hosp, Dept Radiol, Athinoula A Martinos Ctr Biomed Imaging, Charlestown, MA USAUniv Michigan, Dept Obstet & Gynecol, Ann Arbor, MI 48109 USA
Napadow, Vitaly
Harris, Richard E.
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Univ Michigan Hlth Syst, Dept Anesthesiol, Chron Pain & Fatigue Res Ctr, Ann Arbor, MI 48109 USAUniv Michigan, Dept Obstet & Gynecol, Ann Arbor, MI 48109 USA