Development of a Process for Separation of Mogroside V from Siraitia grosvenorii by Macroporous Resins

被引：12
|
作者：
Zhang, Min [2 ]
Yang, Huihua [1 ]
Zhang, Hongyang [3 ]
Wang, Yuerong [3 ]
Hu, Ping [3 ]
机构：
[1] Guilin Univ Elect Technol, Coll Comp Sci & Control, Guilin 541004, Peoples R China
[2] E China Univ Sci & Technol, Sch Pharm, Modern Engn Ctr Tradit Chinese Med, Shanghai 200237, Peoples R China
[3] E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China
来源：
MOLECULES | 2011年 / 16卷 / 09期
基金：
中国国家自然科学基金;
关键词：
mogrosides V; Siraitia grosvenorii; macroporous resins; separation; enrichment;
D O I：
10.3390/molecules16097288
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A separation method was developed for the preparative separation and enrichment of the non-caloric sweetener mogroside V from Siraitia grosvenorii. The adsorption properties of six macroporous resins were evaluated. Results showed that HZ 806 resin offered the best adsorption and desorption capacities. Based on the adsorption experiments on HZ 806, the adsorption data were found to fit the Freundlich model well. The pseudo-second-order kinetic model showed the highest correlation with the experimental results. Separation was performed with deionized water and 40% aqueous ethanol solution as mobile phases. In a typical run, 100 g of herb was processed and 3.38 g of mogroside V with a purity of 10.7% was harvested. This separation method provided a 15.1-fold increase in the purification factor from 0.5% to 10.7%. The present study showed that HZ 806 resins were effective for the separation and enrichment of mogroside V from S. grosvenorii.
引用
收藏
页码：7288 / 7301
页数：14
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