Palladium-Catalyzed Three-Component Coupling Reaction of o-Bromobenzaldehyde, N-Tosylhydrazone, and Methanol

被引：25
|
作者：
Zhu, Lei [1 ]
Ren, Xiaojian [1 ]
Yu, Yinghua [1 ]
Ou, Pengcheng [1 ]
Wang, Zhi-Xiang [3 ]
Huang, Xueliang [1 ,2 ]
机构：
[1] Univ Chinese Acad Sci, Chinese Acad Sci, Key Lab Coal Ethylene Glycol & Related Technol, Ctr Excellence Mol Synth,Fujian Inst Res Struct M, Fuzhou 350002, Fujian, Peoples R China
[2] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
[3] Univ Chinese Acad Sci, Sch Chem Sci, Beijing 100049, Peoples R China
来源：
ORGANIC LETTERS | 2020年 / 22卷 / 05期
关键词：
DIAZOCARBONYL COMPOUNDS; REGIOSPECIFIC SYNTHESIS; MIGRATORY INSERTION; ORTHO-METALATION; ACID; CONSTRUCTION; REAGENTS; BROMIDES; ROUTE;
D O I：
10.1021/acs.orglett.0c00579
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A ligand-controlled palladium-catalyzed three-component reaction of o-bromobenzaldehyde, N-tosylhydrazone, and methanol is described. This reaction uses readily available compounds as starting materials while displaying a broad substrate scope and good functional group compatibility.
引用
收藏
页码：2087 / 2092
页数：6
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