The assembly of yeast mitochondrial ATP synthase: subunit depletion in vivo suggests ordered assembly of the stalk subunits b, OSCP and d

被引：24

作者：

Straffon, AFL ^{[1
]}

Prescott, M ^{[1
]}

Nagley, P ^{[1
]}

Devenish, RJ ^{[1
]}

机构：

[1] Monash Univ, Dept Biochem & Mol Biol, Melbourne, Vic 3168, Australia

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 1998年 / 1371卷 / 02期

基金：

澳大利亚研究理事会;

关键词：

mitochondrion; ATP synthase; stalk region; assembly; subunit depletion; (yeast);

D O I：

10.1016/S0005-2736(98)00034-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The abundance in vivo of each of three subunits b, OSCP and ct, components of the stalk region of the yeast mitochondrial ATP synthase complex, was manipulated by a controlled depletion strategy. Western blots of whole cell lysates were used to study the effect of depletion of each of these subunits on the cellular levels of other subunits of the enzyme complex. A hierarchy of subunit stability was determined and interpreted to indicate the order of assembly of these three subunits of the stalk region. Thus, subunit b is assembled first, followed by OSCP and then by subunit d. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：157 / 162

页数：6

共 44 条

[21] A novel fluorescent marker for assembled mitochondria ATP synthase of yeast - OSCP subunit fused to green fluorescent protein is assembled into the complex in vivo
Prescott, M
Lourbakos, A
Bateson, M
Boyle, G
Nagley, P
Devenish, RJ
FEBS LETTERS, 1997, 411 (01): : 97 - 101
[22] Atco, a yeast mitochondrial complex of Atp9 and Cox6, is an assembly intermediate of the ATP synthase
Ribeiro Franco, Leticia Veloso
Su, Chen-Hsien
Burnett, Julia
Teixeira, Lorisa Simas
Tzagoloff, Alexander
PLOS ONE, 2020, 15 (05):
[23] Assembly-dependent translation of subunits 6 (Atp6) and 9 (Atp9) of ATP synthase in yeast mitochondria
Kabala, Anna M.
Binko, Krystyna
Godard, Francois
Charles, Camille
Dautant, Alain
Baranowska, Emilia
Skoczen, Natalia
Gombeau, Kewin
Bouhier, Marine
Becker, Hubert D.
Ackerman, Sharon H.
Steinmetz, Lars M.
Tribouillard-Tanvier, Deborah
Kucharczyk, Roza
Di Rago, Jean-Paul
GENETICS, 2022, 220 (03)
[24] THE ROLE OF SUBUNIT 4, A NUCLEAR-ENCODED PROTEIN OF THE F0 SECTOR OF YEAST MITOCHONDRIAL ATP SYNTHASE, IN THE ASSEMBLY OF THE WHOLE COMPLEX
PAUL, MF
VELOURS, J
DECHATEAUBODEAU, GA
AIGLE, M
GUERIN, B
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1989, 185 (01): : 163 - 171
[25] Evidence of a subunit 4 (subunit b) dimer in favor of the proximity of ATP synthase complexes in yeast inner mitochondrial membrane
Spannagel, C
Vaillier, J
Arselin, G
Graves, PV
Grandier-Vazeille, X
Velours, J
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1998, 1414 (1-2): : 260 - 264
[26] THE C-TERMINAL POSITIVELY CHARGED REGION OF SUBUNIT-8 OF YEAST MITOCHONDRIAL ATP SYNTHASE IS REQUIRED FOR EFFICIENT ASSEMBLY OF THIS SUBUNIT INTO THE MEMBRANE F0 SECTOR
GRASSO, DG
NERO, D
LAW, RHP
DEVENISH, RJ
NAGLEY, P
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1991, 199 (01): : 203 - 209
[27] Mitochondrial ATP synthase subunit d, a component of the peripheral stalk, is essential for growth and heat stress tolerance in Arabidopsis thaliana
Liu, Tianxiang
Arsenault, Jesse
Vierling, Elizabeth
Kim, Minsoo
PLANT JOURNAL, 2021, 107 (03): : 713 - 726
[28] Time-Delayed In Vivo Assembly of Subunit a into Preformed Escherichia coli FoF1 ATP Synthase
Brockmann, Britta
Hoppmann, Kim Danielle Koop Genannt
Strahl, Henrik
Deckers-Hebestreit, Gabriele
JOURNAL OF BACTERIOLOGY, 2013, 195 (18) : 4074 - 4084
[29] The absence of the mitochondrial ATP synthase delta subunit promotes a slow growth phenotype of rho(-) yeast cells by a lack of assembly of the catalytic sector F-1
Giraud, MF
Velours, J
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 245 (03): : 813 - 818
[30] EACH OF 3 POSITIVELY-CHARGED AMINO-ACIDS IN THE C-TERMINAL REGION OF YEAST MITOCHONDRIAL ATP SYNTHASE SUBUNIT-8 IS REQUIRED FOR ASSEMBLY
PAPAKONSTANTINOU, T
GALANIS, M
NAGLEY, P
DEVENISH, RJ
BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1144 (01) : 22 - 32

← 1 2 3 4 5 →