Emergence in Japan of an imipenem-susceptible, meropenem-resistant Klebsiella pneumoniae carrying blaIMP-6

被引:43
|
作者
Shigemoto, Norifumi [1 ,2 ,3 ]
Kuwahara, Ryuichi [1 ,2 ]
Kayama, Shizuo [1 ,2 ]
Shimizu, Wataru [1 ,2 ,3 ]
Onodera, Makoto [1 ,4 ]
Yokozaki, Michiya [1 ,4 ]
Hisatsune, Junzo [1 ,2 ]
Kato, Fuminori [1 ,2 ]
Ohge, Hiroki [1 ,5 ]
Sugai, Motoyuki [1 ,2 ]
机构
[1] Hiroshima Univ, Project Res Ctr Nosocomial Infect Dis, Minami Ku, Hiroshima 7348551, Japan
[2] Hiroshima Univ, Grad Sch Biomed Sci, Dept Bacteriol, Minami Ku, Hiroshima 7348551, Japan
[3] Hiroshima Univ, Grad Sch Biomed Sci, Dept Surg 1, Minami Ku, Hiroshima 7348551, Japan
[4] Hiroshima Univ Hosp, Clin Lab, Minami Ku, Hiroshima 7348551, Japan
[5] Div Infect Dis, Minami Ku, Hiroshima 7348551, Japan
关键词
Carbapenem resistance; Klebsiella; Metallo-beta-lactamase; ESBL; BETA-LACTAMASE; GENES;
D O I
10.1016/j.diagmicrobio.2011.09.019
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We identified 5 Klebsiella pneumoniae isolates showing high resistance to beta-lactams except imipenem and designated them ISMRK (imipenem-susceptible but meropenem-resistant Klebsiella). They carried the bla(IMP-6) and bla(CTX-M-2) on a self-transmissible plasmid. ISMRK may be falsely categorized as susceptible to carbapenems if imipenem is used to screen carbapenem resistance. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码:109 / 112
页数:4
相关论文
共 50 条
  • [41] Complete Genome Sequence of a Klebsiella pneumoniae Strain Carrying Novel Variant blaKPC-203, Cross-Resistant to Ceftazidime/Avibactam and Cefiderocol, but Susceptible to Carbapenems, Isolated in Italy, 2023
    Amadesi, Stefano
    Bianco, Gabriele
    Secci, Benedetta
    Fasciana, Teresa
    Boattini, Matteo
    Costa, Cristina
    Gaibani, Paolo
    PATHOGENS, 2024, 13 (06):
  • [42] Emergence of a ST307 clone carrying a novel insertion element MITEKpn1 in the mgrB gene among carbapenem-resistant Klebsiella pneumoniae from Moscow, Russia
    Shamina, O., V
    Kryzhanovskaya, O. A.
    Lazareva, A., V
    Alyabieva, N. M.
    Polikarpova, S., V
    Karaseva, O., V
    Mayanskiy, N. A.
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2020, 55 (02)
  • [43] In vitro activity and genomic characterization of KPC-producing Klebsiella pneumoniae clinical blood culture isolates resistant to ceftazidime/avibactam, meropenem/vaborbactam, imipenem/relebactam: an Italian nationwide multicentre observational study (2022-23)
    Bianco, Gabriele
    Boattini, Matteo
    Lupo, Laura
    Ambretti, Simone
    Greco, Rita
    Degl'Innocenti, Linda
    Ranieri, Sofia Chiatamone
    Fasciana, Teresa
    Mazzariol, Annarita
    Gibellini, Davide
    Antonelli, Guido
    Sacco, Federica
    Quirino, Angela
    Farina, Claudio
    Paglietti, Bianca
    Comini, Sara
    Fiamma, Maura
    Broccolo, Francesco
    Cavallo, Rossana
    Costa, Cristina
    Gaibani, Paolo
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2024, 80 (02) : 583 - 592
  • [44] Emergence of the third-generation cephalosporin-resistant hypervirulent Klebsiella pneumoniae due to the acquisition of a self-transferable blaDHA-1-carrying plasmid by an ST23 strain
    Xie, Yingzhou
    Tian, Lijun
    Li, Gang
    Qu, Hongping
    Sun, Jingyong
    Liang, Wei
    Li, Xiaobin
    Wang, Xiaoli
    Deng, Zixin
    Liu, Jialin
    Ou, Hong-Yu
    VIRULENCE, 2018, 9 (01) : 838 - 844
  • [45] A mechanism-based model to describe the emergence of resistance in response to treatment with polymyxin B (PMB), fosfomycin, and meropenem against carbapenem-resistant Klebsiella pneumoniae (CRKP) using an in vitro dynamic infection model (IVDIM)
    Diep, John K.
    Garcia, Estefany
    El-Sheikh, Ahmed O.
    Rao, Gauri G.
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2018, 45 : S129 - S130
  • [46] Emergence of an Extensive Drug Resistant Pseudomonas aeruginosa Strain of Chicken Origin Carrying blaIMP-45, tet(X6), and tmexCD3-toprJ3 on an IncpRBL16 Plasmid
    Dong, Ning
    Liu, Congcong
    Hu, Yanyan
    Lu, Jiayue
    Zeng, Yu
    Chen, Gongxiang
    Chen, Sheng
    Zhang, Rong
    MICROBIOLOGY SPECTRUM, 2022, 10 (06):
  • [47] Successful treatment of a Carbapenem-resistant Klebsiella pneumoniae carrying bla(OXA-48), bla(VIM-2), bla(CMY-2) and bla(SHV-) with high dose combination of imipenem and amikacin
    Hajjej, Zied
    Gharsallah, Hedi
    Naija, Habiba
    Boutiba, Ilhem
    Labbene, Iheb
    Ferjani, Mustapha
    IDCASES, 2016, 4 : 10 - 12
  • [48] Emergence of the third-generation cephalosporin-resistant hypervirulent Klebsiella pneumoniae due to the acquisition of a self-transferable blaDHA-1-carrying plasmid by an ST23 strain (vol 9, pg 838, 2018)
    Xie, Y.
    Tian, L.
    Li, G.
    VIRULENCE, 2018, 9 (01) : 1000 - 1000
  • [49] Emergence of blaNDM-1 associated with the aac(6′)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil
    Lima Scavuzzi, Alexsandra Maria
    Firmo, Elza Ferreira
    de Oliveira, Erica Maria
    de Souza Lopes, Ana Catarina
    REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 2019, 52
  • [50] Emergence of the Novel Aminoglycoside Acetyltransferase Variant aac(6′)-Ib-D179Y and Acquisition of Colistin Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae Due to a Disrupting Mutation in the DNA Repair Enzyme MutS
    Sato, Toyotaka
    Wada, Takayuki
    Nishijima, Suguru
    Fukushima, Yukari
    Nakajima, Chie
    Suzuki, Yasuhiko
    Takahashi, Satoshi
    Yokota, Shin-ichi
    MBIO, 2020, 11 (06):