Is there a relationship between sleep apnoea and microalbuminuria?

被引:0
|
作者
Cihanbeylerden, Melek [1 ]
Yuceege, Melike Bagnu [2 ]
机构
[1] Agri Res & Training Hosp, Agri, Turkey
[2] Diskapi Yildirim Beyazit Res & Training Hosp, Fac Hlth Sci, Ankara, Turkey
关键词
Obstructive sleep apnoea; Microalbuminuria; Endothelial damage; Polysomnography; URINARY ALBUMIN EXCRETION; RENAL-FUNCTION; HYPERTENSION; ADULTS; RISK;
D O I
10.1007/s11325-021-02461-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction Obstructive sleep apnoea (OSA) is a cause of hypoxia, and the correlation between hypoxia and microvascular complications is well known. Microalbuminuria (MAU) is a marker for endovascular dysfunction and an indicator of cardiovascular events and all-cause mortality in the general population. The aim of this study was to investigate the relationship between microvascular damage and the metabolic complications of OSA based on the presence of MAU. Material and method Urinary albumin/creatinine ratio (ACR) and microalbumin level were examined in patients with an apnoea-hypopnoea index (AHI) greater than 5/h (study group) and in patients with an AHI less than 5/h (control group). The exclusion criteria were other possible causes of MAU (hypertension, nephropathy, coronary artery disease, and severe thyroid dysfunction). Results Of 103 patients enrolled, 80 formed the group with OSA and 23 served as controls. According to the AHI values, the patients were divided into four groups as normal, mild, moderate and severe. There was no significant difference between the four groups in terms of the microalbumin level and urinary albumin/creatinine ratio. Conclusion In this study, no significant relationship was found between MAU and sleep apnoea.
引用
收藏
页码:1459 / 1464
页数:6
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