Comment on "Finding reduced Raman spectroscopy fingerprint of skin samples for melanoma diagnosis through machine learning"

This paper comments on the article "Finding reduced Raman spectroscopy fingerprint of skin samples for melanoma diagnosis through machine learning" by D.C. Araujo et al. The authors apply Raman spectroscopy for the classification of benign and malignant skin neoplasms based on their Raman spectra. Despite the high performance of the proposed technique it may provide unreasonably high accuracy because of incorrect cross-validation procedure. To confirm the possibility to discriminate neoplasm skin tissues based on Raman spectra analysis the authors should provide additional data regarding utilized cross-validation procedure.