An efficient copper-catalyzed formation of highly substituted pyrazoles using molecular oxygen as the oxidant

被引：83

作者：

Suri, Mamta ^{[1
]}

Jousseaume, Thierry ^{[1
]}

Neumann, Julia J. ^{[1
]}

Glorius, Frank ^{[1
]}

机构：

[1] Univ Munster, NRW Grad Sch Chem, Inst Organ Chem, D-48149 Munster, Germany

来源：

GREEN CHEMISTRY | 2012年 / 14卷 / 08期

基金：

欧洲研究理事会;

关键词：

N BOND-FORMATION; C-H ACTIVATION; ARYL KETONES; DERIVATIVES; NITRILES; ANILINES; INDOLES; ENAMINONES; INHIBITORS; ARYLATION;

D O I：

10.1039/c2gc35476d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient Cu-catalyzed formation of tetra-substituted pyrazoles is reported. In this atom economic process, readily available enamines and nitriles are reacted by C-C and N-N bond formation. Oxygen has been successfully used as the oxidant, which has important economic and environmental advantages. A broad scope of enamines and nitriles can be utilized in this process.

引用

页码：2193 / 2196

页数：4

共 50 条

[41] Synthesis of Highly Substituted Pyridines through Copper-Catalyzed Condensation of Oximes and α,β-Unsaturated Imines
Tan, Wei Wen
Ong, Yew Jin
Yoshikai, Naohiko
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 56 (28) : 8240 - 8244
[42] Copper-catalyzed oxidative desulfurization-promoted intramolecular cyclization of thioamides using molecular oxygen as an oxidant: An efficient route to five- to seven-membered nitrogen-containing heterocycles
Shibahara, Fumitoshi
Yoshida, Atsunori
Murai, Toshiaki
CHEMISTRY LETTERS, 2008, 37 (06) : 646 - 647
[43] Copper-Catalyzed Annulation of α,β-Unsaturated Ketoximes with Dialkyl Acetylenedicarboxylates for the Synthesis of Highly Substituted Pyridines
He, Shi-Mei
Yang, Yun-Bo
Liu, Lv-Yan
Yu, Ning
Zhou, Yu-Qiang
Zhou, Jia-Hao
Zheng, Mei-Jun
Jin, Xiao-Kun
Jiang, Kun
Wei, Ye
ORGANIC LETTERS, 2025, 27 (05) : 1100 - 1105
[44] Electrochemically enabled copper-catalyzed C-H amination using electricity as an oxidant
Suppan, Kathiravan
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 257
[45] Highly selective copper-catalyzed monoarylation of aniline
Haider, J
Kunz, K
Scholz, U
ADVANCED SYNTHESIS & CATALYSIS, 2004, 346 (07) : 717 - 722
[46] Copper-Catalyzed Oxygenation Approach to Oxazoles from Amines, Alkynes, and Molecular Oxygen
Pan, Jun
Li, Xinyao
Qiu, Xu
Luo, Xiao
Jiao, Ning
ORGANIC LETTERS, 2018, 20 (09) : 2762 - 2765
[47] Copper-catalyzed oxidative heterocyclization by atmospheric oxygen
Bluhm, ME
Ciesielski, M
Görls, H
Döring, M
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2002, 41 (16) : 2962 - 2965
[48] Copper-catalyzed synthesis of α-ketoamides using water and dioxygen as the oxygen source
Xiao, Yuanyuan
Yi, Zijuan
Yu, Xianyong
Xiao, Fang
RSC ADVANCES, 2020, 10 (49) : 29114 - 29118
[49] An Efficient Copper-Catalyzed Carbon-Sulfur Bond Formation Protocol in Water
Ke, Fang
Qu, Yanyang
Jiang, Zhaoqiong
Li, Zhengkai
Wu, Di
Zhou, Xiangge
ORGANIC LETTERS, 2011, 13 (03) : 454 - 457
[50] Highly efficient NaNO2 -: Catalyzed destruction of trichlorophenol using molecular oxygen
Liang, XM
Fu, DM
Liu, RH
Zhang, Q
Zhang, TY
Hu, XQ
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (34) : 5520 - 5523

← 1 2 3 4 5 →