Biosynthesized colloidal silver and gold nanoparticles as emerging leishmanicidal agents: an insight

被引：43

作者：

Ovais, Muhammad ^{[1
,2
,3
,4
]}

Nadhman, Akhtar ^{[5
]}

Khalil, Ali Talha ^{[1
,6
]}

Raza, Abida ^{[2
]}

Khuda, Fazli ^{[7
]}

Sohail, Muhammad Farhan ^{[8
,9
]}

Zakiullah ^{[7
]}

Ul Islam, Nazar ^{[10
]}

Sarwar, Hafiz Shoaib ^{[11
]}

Shahnaz, Gul ^{[11
]}

Ahmad, Irshad ^{[12
]}

Saravanan, Muthupandian ^{[13
]}

Shinwari, Zabta Khan ^{[1
,13
,14
]}

机构：

[1] Quaid I Azam Univ, Fac Biol Sci, Dept Biotechnol, Islamabad 45320, Pakistan

[2] Pakistan Atom Energy Commiss, Natl Inst Lasers & Optron NILOP, Islamabad 44000, Pakistan

[3] Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China

[4] Natl Ctr Nanosci & Technol China, CAS Ctr Excellence Nanosci, Beijing 100190, Peoples R China

[5] CECOS Univ IT & Emerging Sci, Inst Integrat Biosci, Peshawar 25000, Pakistan

[6] Qarshi Univ, Dept Eastern Med & Surg, Lahore, Pakistan

[7] Univ Peshawar, Dept Pharm, Peshawar 25120, Pakistan

[8] Harvard Med Sch, Brigham & Womens Hosp, Biomat Innovat Res Ctr, Dept Med, Cambridge, MA 02139 USA

[9] Riphah Int Univ, Riphah Inst Pharmaceut Sci, Lahore Campus, Lahore 54000, Pakistan

[10] Sarhad Univ Sci & Informat Technol, Dept Pharm, Peshawar 25000, Pakistan

[11] Quaid I Azam Univ, Dept Pharm, Islamabad 45320, Pakistan

[12] KFUPM, Dept Life Sci, Dhahran, Saudi Arabia

[13] Mekelle Univ, Coll Hlth Sci, Inst Biomed Sci, Dept Med Microbiol & Immunol, Mekelle 1871, Ethiopia

[14] PAS, Islamabad 44000, Pakistan

来源：

NANOMEDICINE | 2017年 / 12卷 / 24期

关键词：

green synthesis; leishmaniasis; nanomedicine; phyto-nanotechnology; silver and gold nanoparticles; ZINC-OXIDE NANOPARTICLES; ANTILEISHMANIAL EFFICACY; BIOLOGICAL SYNTHESIS; DRUG-RESISTANCE; GREEN SYNTHESIS; PLANTS; NANOBIOTECHNOLOGY; ANTIBACTERIAL; PAROMOMYCIN; MECHANISMS;

D O I：

10.2217/nnm-2017-0233

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Many recent key innovations in nanotechnology have greatly fascinated scientists to explore new avenues in treatment and diagnosis of emerging diseases. Due to extensive utilization of metallic nanoparticles (NPs) in diverse biomedical applications, scientists are looking forward to green synthesis of NPs as safer, simple, fast, and low-cost method over chemical and physical methods. Due to enriched phytochemistry, no need for maintenance and ready availability, plants are preferred for green synthesis of silver (Ag-NPs) and gold NPs (AuNPs). Recently, several researchers have exploited these biogenic NPs as potential antileishmanial agents. The current article is focused to mechanistically explain the antileishmanial activity of biogenic AuNPs and AgNPs with a futuristic discussion on the faith of these particles as emerging antileishmanial agents.

引用

页码：2807 / 2819

页数：13

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