A case report of clozapine augmentation with granulocyte colony stimulating factor (G-CSF)

被引:3
|
作者
Broughton, Trevor [1 ]
Millward, Tim [1 ]
Geelan, Steve [1 ]
机构
[1] E England Forens Mental Hlth Serv, Leicester LE5 0LE, Leics, England
来源
关键词
clozapine; neutropenia; granulocyte colony stimulating factor; INDUCED NEUTROPENIA; RECHALLENGE; LITHIUM; TERM;
D O I
10.1080/14789949.2011.633096
中图分类号
DF [法律]; D9 [法律];
学科分类号
0301 ;
摘要
For some patients clozapine represents the only option for controlling the debilitating symptoms of schizophrenia. More tragic are those cases where previously successful treatment with clozapine is withdrawn as a result of blood dyscrasia. In this article, the authors describe such a case. In this instance it was possible to continue treatment with clozapine to good effect by using granulocyte colony stimulating factor (G-CSF) as an adjunct. This article further explores the decision-making process and the clinical evidence behind this approach.
引用
收藏
页码:125 / 133
页数:9
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