The Detection of Cardiac Adrenocorticotropic Hormone-Secreting Neuroendocrine Tumor With the Help of 68Ga-DOTATATE PET/CT

Ectopic adrenocorticotropic hormone Cushing syndrome is a relatively rare condition. We present the case of a 39-year-old man with ectopic adrenocorticotropic hormone Cushing syndrome due to a cardiac neuroendocrine tumor (NET), which was localized with the help of Ga-68-DOTATATE. F-18-FDG PET/CT revealed a hypermetabolic lesion in the heart, while the distinction between physiological and pathological FDG uptake is difficult. Ga-68-DOTATATE PET/CT revealed focal uptake corresponding to the cardiac focus found on FDG PET/CT, providing evidence of cardiac NET. This case illustrates that Ga-68-DOTATATE could play a role in the evaluation of cardiac NET as it lacks significant physiological myocardial uptake.