Essential Oil from the Leaves of Annona vepretorum: Chemical Composition and Bioactivity

被引：0

作者：

Costa, Emmanoel Vilaca ^{[1
]}

Dutra, Livia Macedo ^{[1
]}

de Lima Nogueira, Paulo Cesar ^{[1
]}

de Souza Moraes, Valeria Regina ^{[1
]}

Salvador, Marcos Jose ^{[2
]}

Gonzaga Ribeiro, Luis Henrique ^{[3
]}

Gadelha, Fernanda Ramos ^{[3
]}

机构：

[1] Univ Fed Sergipe, Dept Chem, BR-49100000 Sao Cristovao, Sergipe, Brazil

[2] Univ Estadual Campinas, Dept Plant Biol, BR-13083862 Sao Paulo, Brazil

[3] Univ Estadual Campinas, Dept Biochem, BR-13083862 Sao Paulo, Brazil

来源：

NATURAL PRODUCT COMMUNICATIONS | 2012年 / 7卷 / 02期

基金：

巴西圣保罗研究基金会;

关键词：

Annona vepretorum; Essential oil composition; Biological activity; TRYPANOSOMA-CRUZI; ANTILEISHMANIAL ACTIVITY; ALKALOIDS; DITERPENOIDS; FOETIDA; L;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The essential oil from the leaves of Annona vepretorun was obtained by hydrodistillation using a Clevenger-type apparatus and analyzed by GC-MS and GC-FID. Eighteen compounds representing 98.1% of the crude essential oil were identified. The major compounds identified were bicyclogermacrene (43.7%), spathulenol (11.4%), alpha-felandrene (10.0%), alpha-pinene (7.1%), (E)-(beta-ocimene (6.8%), germacrene D (5.8%), and p-cymene (4.2%). The trypanocidal activity against Trypanosoma cruzi epimastigote forms, as well as, the antimicrobial and antioxidant proprieties was investigated. The essential oil showed a potent trypanocidal activity with IC50 value of 31.9 +/- 1.3 mu g.mL(-1). For antimicrobial activity, the best result was observed against Candida tropicalis with a MIC value of 100 mu g.mL(-1). For antioxidant capacity the essential oil showed weak activity.

引用

页码：265 / 266

页数：2

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