Essential Oil from the Leaves of Annona vepretorum: Chemical Composition and Bioactivity

被引：0
|
作者：
Costa, Emmanoel Vilaca [1 ]
Dutra, Livia Macedo [1 ]
de Lima Nogueira, Paulo Cesar [1 ]
de Souza Moraes, Valeria Regina [1 ]
Salvador, Marcos Jose [2 ]
Gonzaga Ribeiro, Luis Henrique [3 ]
Gadelha, Fernanda Ramos [3 ]
机构：
[1] Univ Fed Sergipe, Dept Chem, BR-49100000 Sao Cristovao, Sergipe, Brazil
[2] Univ Estadual Campinas, Dept Plant Biol, BR-13083862 Sao Paulo, Brazil
[3] Univ Estadual Campinas, Dept Biochem, BR-13083862 Sao Paulo, Brazil
来源：
NATURAL PRODUCT COMMUNICATIONS | 2012年 / 7卷 / 02期
基金：
巴西圣保罗研究基金会;
关键词：
Annona vepretorum; Essential oil composition; Biological activity; TRYPANOSOMA-CRUZI; ANTILEISHMANIAL ACTIVITY; ALKALOIDS; DITERPENOIDS; FOETIDA; L;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The essential oil from the leaves of Annona vepretorun was obtained by hydrodistillation using a Clevenger-type apparatus and analyzed by GC-MS and GC-FID. Eighteen compounds representing 98.1% of the crude essential oil were identified. The major compounds identified were bicyclogermacrene (43.7%), spathulenol (11.4%), alpha-felandrene (10.0%), alpha-pinene (7.1%), (E)-(beta-ocimene (6.8%), germacrene D (5.8%), and p-cymene (4.2%). The trypanocidal activity against Trypanosoma cruzi epimastigote forms, as well as, the antimicrobial and antioxidant proprieties was investigated. The essential oil showed a potent trypanocidal activity with IC50 value of 31.9 +/- 1.3 mu g.mL(-1). For antimicrobial activity, the best result was observed against Candida tropicalis with a MIC value of 100 mu g.mL(-1). For antioxidant capacity the essential oil showed weak activity.
引用
收藏
页码：265 / 266
页数：2
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