Venom Evolution: Gene Loss Shapes Phenotypic Adaptation

被引:13
|
作者
Casewell, Nicholas R. [1 ]
机构
[1] Univ Liverpool, Liverpool Sch Trop Med, Alistair Reid Venom Res Unit, Dept Parasitol, Pembroke Pl, Liverpool L3 5QA, Merseyside, England
关键词
SNAKE-VENOM; SYSTEM; MECHANISMS; ORIGIN; GENOME;
D O I
10.1016/j.cub.2016.07.082
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Snake venoms are variable protein mixtures with a multitude of bioactivities. New work shows, surprisingly, that it is the loss of toxin-encoding genes that strongly influences venom function in rattlesnakes, highlighting how gene loss can underpin adaptive phenotypic change.
引用
收藏
页码:R849 / R851
页数:3
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