Knocking Down Delta-5 Desaturase and Exploiting High Expression Level of COX-2 to Inhibit Cancer Migration and Invasion

被引：1
|
作者：
Yang, Xiaoyu [1 ]
Xu, Yi [1 ]
Miskimins, Keith W. [2 ]
Qian, Steven Y. [1 ]
机构：
[1] North Dakota State Univ, Fargo, ND USA
[2] Sanford Res, Canc Biol Res Ctr, Sioux Falls, SD USA
来源：
FREE RADICAL BIOLOGY AND MEDICINE | 2016年 / 100卷
关键词：
D O I：
10.1016/j.freeradbiomed.2016.10.351
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
310
引用
收藏
页码：S133 / S133
页数：1
相关论文
共 50 条
  • [31] Insulin-like growth factor binding protein-4 inhibits cell growth, migration and invasion, and downregulates COX-2 expression in A549 lung cancer cells
    Li, Weiwen
    Sun, Debin
    Lv, Zhuqing
    Wei, Yueqiu
    Zheng, Liyun
    Zeng, Tingting
    Zhao, Jialu
    CELL BIOLOGY INTERNATIONAL, 2017, 41 (04) : 384 - 391
  • [32] Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion
    Zheng, Hao
    Li, Ying
    Wang, Yuzhong
    Zhao, Haixia
    Zhang, Jing
    Chai, Hongyan
    Tang, Tian
    Yue, Jiang
    Guo, Austin M.
    Yang, Jing
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 280 (01) : 10 - 20
  • [33] The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer
    Kemilainen, Heidi
    Huhtinen, Kaisa
    Auranen, Annika
    Carpen, Olli
    Strauss, Leena
    Poutanen, Matti
    ONCOLOGY, 2018, 94 (04) : 233 - 242
  • [34] EBV down-regulates COX-2 expression via TRAF2 and ERK signal pathway in EBV-associated gastric cancer
    Qi, Yi-Fan
    Liu, Mengyang
    Zhang, Yan
    Liu, Wen
    Xiao, Hua
    Luo, Bing
    VIRUS RESEARCH, 2019, 272
  • [35] High density oligonucleotide arrays demonstrate differential gene expression in colon cancer cells following COX-2 inhibition
    Byrne, SM
    Doherty, GA
    Scully, GM
    Murray, FE
    Fitzgerald, DJ
    GUT, 2004, 53 : A18 - A19
  • [36] Cox-2 Expression in High-grade Breast Cancer: Evidence for Prognostic Significance in the Subset of Triple-negative Breast Cancer
    Chikman, B.
    Lavy, R.
    Kapiev, A.
    Halevy, A.
    ANNALS OF SURGICAL ONCOLOGY, 2014, 21 : S66 - S67
  • [37] Knocking Out SST Gene of BGC823 Gastric Cancer Cell by CRISPR/Cas9 Enhances Migration, Invasion and Expression of SEMA5A and KLF2
    Chen, Wei
    Ding, Ruixian
    Tang, Jinlu
    Li, Haodong
    Chen, Chonghua
    Zhang, Yaru
    Zhang, Qinxian
    Zhu, Xiaoyan
    CANCER MANAGEMENT AND RESEARCH, 2020, 12 : 1313 - 1321
  • [38] Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells
    Kim, Sangmin
    Kim, Sung Hoon
    Hur, Sung Mo
    Lee, Se-Kyung
    Kim, Wan Wook
    Kim, Jee Soo
    Kim, Jung-Han
    Choe, Jun-Ho
    Nam, Seok Jin
    Lee, Jeong Eon
    Yang, Jung-Hyun
    JOURNAL OF ETHNOPHARMACOLOGY, 2009, 126 (02) : 252 - 257
  • [39] The effect of miR-217 on the migration and invasion ability of cervical cancer cells by down-regulating the expression level of PTPN9
    Li, Hua
    Ma, Ling
    Ma, Yongping
    Ding, Qilan
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 127 : 113 - 113
  • [40] Desmocollin 2 suppresses lung cancer cell migration and invasion through down-regulation of NDRG1 expression
    Hsu, Yu-Chih
    Ou, Po-Chun
    Chen, Yu-Yi
    Tsai, Meng-Feng
    CANCER RESEARCH, 2014, 74 (19)
12345