Neonatal reversible focal cerebral ischemia: a new model

被引：73
|
作者：
Derugin, N
Ferriero, DM
Vexler, ZS
机构：
[1] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Neurosurg, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Pediat, San Francisco, CA 94143 USA
来源：
NEUROSCIENCE RESEARCH | 1998年 / 32卷 / 04期
关键词：
stroke; neonate; middle cerebral artery occlusion; reversible cerebral ischemia; TTC;
D O I：
10.1016/S0168-0102(98)00096-0
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
While numerous animal models exist for studying neonatal brain injury after cerebral ischemia-hypoxia, an adequate model for assessing reversible focal ischemia in the neonatal rat has not been reported. This paper describes in detail a new surgical procedure for creating a non-hemorrhagic, reperfused focal ischemic lesion in the neonatal, 7-day-old rat pup. (C) 1998 Published by Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：349 / 353
页数：5
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