Open chromatin and hypertranscription in embryonic stem cells

被引：13
|
作者：
Turner, Bryan M. [1 ]
机构：
[1] Univ Birmingham, Sch Med, Inst Biomed Res, Birmingham B15 2TT, W Midlands, England
来源：
CELL STEM CELL | 2008年 / 2卷 / 05期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/j.stem.2008.04.006
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
In this issue of Cell Stem Cell, Efroni et al. (2008) use tiling microarrays to reveal genome-wide hypertranscription in mouse embryonic stem cells (ESCs), including expression of normally silent, noncoding regions. Hypertranscription may reflect the unusual "open" structure of ESC chromatin.
引用
收藏
页码：408 / 410
页数：3
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