[1] Univ Genoa, Dept Hlth Sci, Genoa, Italy
[2] ASST Spedali Civili Brescia, Ctr Sclerosi Multipla, Brescia, Italy
[3] IRCCS Osped San Raffaele, Dept Neurol, Multiple Sclerosis Ctr, Milan, Italy
[4] ASST Papa Giovanni XXIII, Dept Neurol, Bergamo, Italy
[5] ASST Papa Giovanni XXIII, Multiple Sclerosis Ctr, Bergamo, Italy
[6] Osped Guglielmo Saliceto, Multiple Sclerosis Ctr, Piacenza, Italy
[7] Univ Hosp San Luigi, Dept Neurol, Reg Referral Multiple Sclerosis, Orbassano, Italy
[8] Univ Bari, Dept Basic Med Sci Neurosci & Sense Organs, Bari, Italy
[9] Italian Multiple Sclerosis Fdn, Res Dept, Genoa, Italy
[10] Univ Campania, Dept Adv Med & Surg Sci, Naples, Italy
[11] IRCCS Osped San Raffaele, Inst Expt Neurol, Milan, Italy
[12] Univ Catania, Policlin Catania, Ctr Sclerosi Multipla, Catania, Italy
[13] Sapienza Univ Rome, Dept Neurosci Mental Hlth & Sensory Organs, Rome, Italy