Hypoglycemic and antidiabetic activities on the stem bark aqueous and ethanol extracts of Musanga cecropioides in normal and alloxan-induced diabetic rats

被引：17
|
作者：
Adeneye, A. A.
Ajagbonna, O. P.
Ayodele, O. W.
机构：
[1] Lagos State Univ Med, Dept Pharmacol, Ikeja, Nigeria
[2] Usman Danfodiyo Univ, Fac Med Vet, Dept Vet Physiol & Pharmacol, Sokoto, Nigeria
[3] Lagos State Univ, Fac Sci, Dept Biochem, Lagos, Nigeria
来源：
FITOTERAPIA | 2007年 / 78卷 / 7-8期
关键词：
Musanga cecropioides; hypoglycemic; antidiabetic; stem bark;
D O I：
10.1016/j.fitote.2007.05.001
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Daily oral administration of the aqueous and ethanolic extracts of Musanga cecropioides stem bark in normal and diabetic rats at doses of 250, 500 and 1000 mg/kg/day, for 14 days significantly lowered the fasting plasma glucose levels in normal and alloxan-induced diabetic rats in dose-dependent fashion. The ethanol extract induced more significant antidiabetic effect than the aqueous extract. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码：502 / 505
页数：4
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