Myocardial ischemia in patients with dilated cardiomyopathy

被引：20
|
作者：
Fang, Wei [1 ]
Zhang, Jian [2 ]
He, Zuo-Xiang [1 ,3 ,4 ]
机构：
[1] Chinese Acad Med Sci, Dept Nucl Med, Cardiovasc Inst, Beijing 100037, Peoples R China
[2] Chinese Acad Med Sci, Dept Cardiol, Cardiovasc Inst, Beijing 100037, Peoples R China
[3] Chinese Acad Med Sci, Fu Wai Hosp, Beijing 100037, Peoples R China
[4] Peking Union Med Coll, Beijing 100037, Peoples R China
来源：
NUCLEAR MEDICINE COMMUNICATIONS | 2010年 / 31卷 / 11期
关键词：
dilated cardiomyopathy; heart failure; left ventricular dysfunction; myocardial ischemia; CORONARY-ARTERY-DISEASE; BLOOD-FLOW RESERVE; HEART-FAILURE; PERFUSION RESERVE; WALL-MOTION; FATTY-ACID; SPECT; PET; MICROCIRCULATION; ABNORMALITIES;
D O I：
10.1097/MNM.0b013e32833f393f
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Dilated cardiomyopathy (DCM) is characterized by ventricular chamber enlargement and systolic dysfunction with normal ventricular wall thickness. More recent studies have shown that the coronary microcirculation may be directly affected in cardiomyopathies. Left ventricular regional myocardial perfusion, wall motion, and metabolism abnormalities are often present in patients with DCM. These data support the possibility that myocardial ischemia may play an important role in the development of DCM and have important prognostic value in patients with DCM. We need to pay attention to the assessment of myocardial blood flow and myocardial ischemia in patients with DCM. Furthermore, anti-ischemic therapy may improve left ventricular function and clinical outcomes in patients with heart failure resulted from DCM. Nucl Med Commun 31: 981-984 (C) 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins.
引用
收藏
页码：981 / 984
页数：4
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