Recurrent severe bleeding from gastrointestinal angiodysplasia in a patient with von Willebrand's disease, controlled with recombinant factor VIIa

被引：34
|
作者：
Meijer, K
Peters, FTM
van der Meer, J
机构：
[1] Univ Groningen Hosp, Div Haemostasis Thrombosis & Rheol, NL-9713 GZ Groningen, Netherlands
[2] Univ Groningen Hosp, Dept Gastroenterol & Hepatol, NL-9713 GZ Groningen, Netherlands
来源：
BLOOD COAGULATION & FIBRINOLYSIS | 2001年 / 12卷 / 03期
关键词：
angiodysplasia; recombinant factor VIIa; von Willebrand's disease;
D O I：
10.1097/00001721-200104000-00008
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A patient with von Willebrand's disease had recurrent gastrointestinal bleeding from angiodysplasia, with inadequate response to von Willebrand factor substitution, medical and endoscopic treatment, and resection of affected bowel. Frequent blood transfusions were required. She started home treatment with recombinant activated factor VII (rFVIIa) at the onset of bleeding, in addition to her standard therapy. From then on, bleeds could be controlled rapidly and no more blood transfusions were needed. We conclude that rFVIIa is effective in this case of angiodysplasia and might be a therapeutic option in similar patients. Blood Coagul Fibrinolysis 12:211-213 (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码：211 / 213
页数：3
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