Monitoring angiogenesis in human melanoma xenografts using contrast-enhanced ultrasound

被引:0
|
作者
Ro, RJ [1 ]
Forsberg, F [1 ]
Liu, JB [1 ]
James, KM [1 ]
Potoczek, M [1 ]
Lewin, PA [1 ]
Nazarian, LN [1 ]
机构
[1] Drexel Univ, Sch Biomed Engn Sci & Hlth Syst, Philadelphia, PA 19104 USA
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中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
In mice implanted with human melanoma xenografts, this study set out to determine if a correlation exists between noninvasive contrast-enhanced ultrasound measures of tumor neovascularity with invasive histologic specimens stained with angiogenesis markers CD31, COX-2, and VEGF. Results indicate that ultrasound, in conjunction with the use of contrast media, may provide a noninvasive marker for angiogenesis.
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页码:520 / 523
页数:4
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