A flip-flop switch in polarity signaling

被引：2

作者：

Menon, Anant K. ^{[1
]}

机构：

[1] Weill Cornll Med Coll, Dept Biochem, New York, NY 10065 USA

来源：

DEVELOPMENTAL CELL | 2007年 / 13卷 / 05期

关键词：

YEAST PLASMA-MEMBRANE; CELL POLARITY; FLIPPASES;

D O I：

10.1016/j.devcel.2007.10.008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The Rho GTPase Cdc42 is essential for polarized growth of budding yeast. Temporal control of Cdc42 depends partly on the activity of its GTPase-activating proteins (GAPs). In this issue of Developmental Cell, Saito et al. report that Cdc42 GAP activity is regulated by the phospholipid composition of the bud-tip membrane, under control of the phospholipid flippases Lem3-Dnf1 and Lem3-Dnf2.

引用

页码：607 / 608

页数：2

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