Targeted blood brain barrier opening induces focal microglia/macrophage activation and affects brain stiffness in experimental autoimmune encephalomyelitis

被引:0
|
作者
Schregel, K. [1 ,2 ]
Baufeld, C. [3 ]
Palotai, M. [2 ]
Meroni, R. [4 ]
Fiorina, P. [4 ,5 ]
Wuerfel, J. [6 ,7 ,8 ,9 ]
Zhang, Y. [2 ]
Sinkus, R. [10 ,11 ]
Patz, S. [2 ]
McDannold, N. [2 ]
White, P. J. [2 ]
Guttmann, C. R. G. [2 ]
机构
[1] Univ Med Ctr Gottingen, Inst Neuroradiol, Gottingen, Germany
[2] Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA USA
[3] Harvard Med Sch, Brigham & Womens Hosp, Dept Neurol, Ann Romney Ctr Neurol Dis, Boston, MA USA
[4] Harvard Med Sch, Boston Childrens Hosp, Nephrol Div, Boston, MA USA
[5] Univ Milan, Dept Biomed & Clin Sci L Sacco, Int Ctr T1D, Pediat Clin Res Ctr,Fdn Romeo & Enrica Invernizzi, Milan, Italy
[6] MIAC AG Basel, Basel, Switzerland
[7] Qbig, Basel, Switzerland
[8] Univ Basel, Dept Biomed Engn, Basel, Switzerland
[9] Charite Univ Med Berlin, NeuroCure, Berlin, Germany
[10] Kings Coll London, Div Imaging Sci & Biomed Engn, London, England
[11] Univ Paris 13, Univ Paris Diderot, LVTS, Inserm,U1148, Paris, France
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
P1060
引用
收藏
页码:585 / 586
页数:2
相关论文
共 50 条
  • [31] The action of TH17 cells on blood brain barrier in multiple sclerosis and experimental autoimmune encephalomyelitis
    Balasa, Rodica
    Barcutean, Laura
    Balasa, Adrian
    Motataianu, Anca
    Roman-Filip, Corina
    Manu, Doina
    HUMAN IMMUNOLOGY, 2020, 81 (05) : 237 - 243
  • [32] Blockade of Arginine Vasopressin receptors prevents blood-brain barrier breakdown in Experimental Autoimmune Encephalomyelitis
    Vinuela-Berni, Veronica
    Gomez-Gonzalez, Beatriz
    Quintanar-Stephano, Andres
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [33] Protein kinase C β as a therapeutic target stabilizing blood brain barrier disruption in experimental autoimmune encephalomyelitis
    Lanz, T. V.
    Osswald, M.
    Opitz, C. A.
    Gaikwad, S.
    Becker, S.
    Litzenburger, U.
    Sahm, F.
    Ott, M.
    Bittner, S.
    Schuhmann, M. K.
    Iwantscheff, S.
    Grabitz, C.
    Mittelbronn, M.
    von Deimling, A.
    Meuth, S. G.
    Winkler, F.
    Wick, W.
    Platten, M.
    MULTIPLE SCLEROSIS JOURNAL, 2013, 19 (11) : 69 - 70
  • [34] Blockade of Arginine Vasopressin receptors prevents blood-brain barrier breakdown in Experimental Autoimmune Encephalomyelitis
    Verónica Viñuela-Berni
    Beatriz Gómez-González
    Andrés Quintanar-Stephano
    Scientific Reports, 10
  • [35] The effects of fasudil on the permeability of the rat blood-brain barrier and blood-spinal cord barrier following experimental autoimmune encephalomyelitis
    Huang, X. N.
    Fu, J.
    Wang, W. Z.
    JOURNAL OF NEUROIMMUNOLOGY, 2011, 239 (1-2) : 61 - 67
  • [36] Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis
    Lu, Lisen
    Qi, Shuhong
    Chen, Yuzhou
    Luo, Haiming
    Huang, Songlin
    Yu, Xiang
    Luo, Qingming
    Zhang, Zhihong
    BIOMATERIALS, 2020, 245
  • [37] Targeted opening of the blood brain barrier by ALA mediated photodynamic therapy
    Hirschberg, Henry
    Peng, Qian
    Uzal, Francisco A.
    Chighvinadze, David
    Zhang, Michelle J.
    Madsen, Steen J.
    12TH WORLD CONGRESS OF THE INTERNATIONAL PHOTODYNAMIC ASSOCIATION: PHOTODYNAMIC THERAPY: BACK TO THE FUTURE, 2009, 7380
  • [38] Neuroimmunological Blood Brain Barrier Opening in Experimental Cerebral Malaria
    Nacer, Adela
    Movila, Alexandru
    Baer, Kerstin
    Mikolajczak, Sebastian A.
    Kappe, Stefan H. I.
    Frevert, Ute
    PLOS PATHOGENS, 2012, 8 (10)
  • [39] A low molecular weight copper chelator crosses the blood-brain barrier and attenuates experimental autoimmune encephalomyelitis
    Offen, D
    Gilgun-Sherki, Y
    Barhum, Y
    Benhar, M
    Grinberg, L
    Reich, R
    Melamed, E
    Atlas, D
    JOURNAL OF NEUROCHEMISTRY, 2004, 89 (05) : 1241 - 1251
  • [40] Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis
    Lanz, Tobias V.
    Becker, Simon
    Osswald, Matthias
    Bittner, Stefan
    Schuhmann, Michael K.
    Opitz, Christiane A.
    Gaikwad, Sadanand
    Wiestler, Benedikt
    Litzenburger, Ulrike M.
    Sahm, Felix
    Ott, Martina
    Iwantscheff, Simeon
    Grabitz, Carl
    Mittelbronn, Michel
    von Deimling, Andreas
    Winkler, Frank
    Meuth, Sven G.
    Wick, Wolfgang
    Platten, Michael
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (36) : 14735 - 14740